Characteristics of the phenotypes from cluster analysis
| Phenotype | ||||
| Characteristics | 1 (n=16, 20.8%) | 2 (n=52, 67.5%) | 3 (n=9, 11.7%) | p Value |
| Soft drusen | 56.3 (29.9 to 80.2) | 34.6 (22.0 to 49.1) | 0.0 (0 to 33.6) | 0.013 |
| RPD | 50.0 (24.7 to 75.3) | 80.8 (67.5 to 90.4) | 100 (66.4 to 100) | 0.012 |
| Foveal atrophy | 100 (79.4 to 100) | 0.00 (0 to 6.8) | 0.00 (0 to 33.6) | <0.001 |
| High FAF | 12.5 (1.6 to 38.3) | 73.1 (59.0 to 84.4) | 88.9 (51.8 to 99.7) | <0.001 |
| Greyish FAF appearance | 0.0 (0 to 20.6) | 0.0 (0 to 6.8) | 100 (66.4 to 100) | <0.001 |
| SFCT (µm) | 197 (118 to 253) | 134 (82 to 179) | 51 (26 to 60) | 0.0001 |
| Area growth rate (mm2/year) | 0.63 (0.32 to 1.32) | 1.91 (1.27 to 2.59) | 1.73 (1.24 to 2.06) | 0.0005 |
| Linear growth rate (mm/year) | 0.17 (0.09 to 0.32) | 0.33 (0.20 to 0.43) | 0.32 (0.24 to 0.42) | 0.022 |
Results are shown as percentage (95% CI) for categorical variables and median (25th and 75th percentiles) for quantitative variables. The p value corresponds to the comparison between the three groups.
FAF, fundus autofluorescence; RPD, high reticular pseudodrusen load; SFCT, subfoveal choroidal thickness.