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Differential permeance of retina and retinal pigment epithelium to water: implications for retinal adhesion

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Abstract

Water movement from the vitreous to the choroid would tend to maintain retinal apposition, if the retina were less permeable than the retinal pigment epithelium (RPE). We used a rabbit model, to test the relative permeability of retina and RPE to tritiated water. The retina was found less permeable than the RPE. This result suggests the presence of a hydrostatic pressure gradient across the retina which could enhance apposition of retina to the RPE.

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Kirchhof, B., Ryan, S.J. Differential permeance of retina and retinal pigment epithelium to water: implications for retinal adhesion. Int Ophthalmol 17, 19–22 (1993). https://doi.org/10.1007/BF00918862

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