Abstract
Fifty-eight prematurely born children (gestational age ≤ 32 weeks) were studied at the age of 5 years. The ophthalmological examination was part of an extensive neurodevelopmental evaluation. The eye study revealed significant hyperopia (≽ + 2.0) in 22.4%, myopia (≥ − 1.0 D) in 8.6%, astigmatism (≥ 1.0 D) in 12.1 %, and anisometropia (≥ 1.0 D) in 12.1 %. The myopic refractive error was high in all of the cases: from − 6.0 to −14.0 D. Manifest strabismus was found in 24.2% and significant visual impairment or blindness in 6.9%. Optic atrophy and cicatricial retinopathy of prematurity were the main causes for severe visual defects. In the randomly selected full-term children of the same age, significant hyperopia was seen in 14.3%, astigmatism in 5.4% and strabismus in 1.8%. The pattern of the eye findings was different in the preterm children compared with those born at term.
Similar content being viewed by others
References
Archambault P, Gomolin JES (1987) Incidence of retinopathy of prematurity among infants weighing 2000 g or less at birth. Can J Ophthalmol 22:218–220
Ben Sira I, Nissenkorn I, Kremer I (1988) Retinopathy of prematurity. Surv Ophthalmol 33:1–16
Brown DR, Milley JR, Ripepi UJ, Biglan AW (1987) Retinopathy of prematurity. Risk factors in a five-year cohort of critically ill premature neonates. Am J Dis Child 141:154–160
Cats BP, Tan KEWP (1989) Prematures with and without regressed retinopathy of prematurity: comparison of long-term (6–10 years) ophthalmological morbidity. J Pediatr Ophthalmol Strabismus 26:271–275
Curtin BJ (1985) Myopia of prematurity. In: Curtin BJ (ed) The myopias. Basic science and clinical management. Harper & Row, Philadelphia, pp 439–448
Duke-Elder Sir S, Abrams D (1970) Ophthalmic optics and refraction. In: Duke-Elder Sir S (ed) System of ophthalmology, vol V. Henry Kimpton, London, pp 234–239
Fielder AR, Moseley MJ, Ng YK (1988) The immature visual system and premature birth. Br Med Bull 44:1093–1118
Fledelius H (1976) Prematurity and the eye. Ophthalmic 10-year follow-up of children of low and normal birth weight. Thesis. Acta Ophthalmol (Copenh) [Suppl] 128
Fledelius HC (1983) Is myopia getting more frequent? A crosssectional study of 1416 Danes aged 16+. Acta Ophthalmol 61:545–559
Fledelius H (1990) Ocular features other than retinopathy of prematurity in the pre-term infant. Acta Ophthalmol 68:214–217
Fledelius H (1990) Retinopathy of prematurity. Clinical findings in a Danish county 1982–87. Acta Ophthalmol 68:209–213
Gallo JE, Lennerstrand G (1991) A population-based study of ocular abnormalities in premature children aged 5 to 10 years. Am J Ophthalmol 111:539–547
Gallo JE, Holmström G, Kugelberg U, Hedquist B, Lennerstrand G (1991) Regressed retinopathy of prematurity and its sequelae in children aged 5–10 years. Br J Ophthahnol 75:527–531
Gerhard JP, Willard D, Risse JF, Kuss JJ, Messer J (1978) Avenir visuel du prématuré. Ophthalmologica 177:293–303
Gibson NA, Fielder AR, Trounce JQ, Levene MI (1990) Ophthalmic findings in infants of very low birth weight. Dev Med Child Neurol 32:7–13
Keith CG, Kitchen WH (1983) Ocular morbidity in infants of very low birth weight. Br J Ophthalmol 67:302–305
Laatikainen L, Erkkild H (1980) Refractive errors and other ocular findings in school children. Acta Ophthalmol 58:129–136
Lennerstrand G, Gallo JE (1989) Prevalence of refractive errors and ocular motility disorders in 5- to 10-year-old Swedish children born prematurely or at full term. Acta Ophthalmol 67:717–718
Mäntyjärvi M (1983) Incidence of myopia in a population of Finnish school children. Acta Ophthalmol 61:417–423
Mäntyjärvi M, Nousiainen I (1988) Refraction and accommodation in diabetic school children. Acta Ophthalmol 66:267–271
Mohindra I, Held R (1981) Refraction in humans from birth to five years. In: Fledelius HC, Alsbirk PH, Goldschmidt E (eds) Third International Conference on Myopia [Doc Ophthalmol Proc Ser 28]. Junk, The Hague, pp 19–27
Ng YK, Fielder AR, Levene MI, Trounce JQ, McLellan N (1989) Are severe acute retinopathy of prematurity and severe periventricular leucomalacia both ischaemic insults? Br J Ophthalmol 73:111–114
Tasman W (1979) Late complications of retrolental fibroplasia. Ophthalmology 86:1724–1740
Trese MT (1991) Management of retinopathy of prematurity. Curr Opin Ophthalmol 2:324–329
Wiesel TN, Raviola E (1977) Myopia and eye enlargement after neonatal lid fusion in monkeys. Nature 266:66–68
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tuppurainen, K., Herrgård, E., Martikainen, A. et al. Ocular findings in prematurely born children at 5 years of age. Graefe's Arch Clin Exp Ophthalmol 231, 261–266 (1993). https://doi.org/10.1007/BF00919102
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00919102