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Asymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucoma

  • Clinical Investigation
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Abstract

Purpose

To investigate interocular differences in retrobulbar flow velocities in patients with asymmetric glaucomatous visual field loss.

Methods

Twenty-five patients with primary open-angle glaucoma (POAG) and asymmetric visual field loss were included in this study. Asymmetric visual field loss was defined as a difference of the global index mean deviation (MD) >6 dB between the two eyes. Flow velocities (peak systolic velocity PSV and end-diastolic velocity EDV) and resistive indices (RI) of the ophthalmic artery (OA), central retinal artery (CRA), and nasal and temporal posterior ciliary arteries were measured by means of colour Doppler imaging.

Results

MD of eyes with more severe glaucomatous visual field loss was −18.3±7.8 dB vs −6.8±5.5 dB (p<0.0001) in the less affected eyes. The PSV and the EDV of the CRA and the PSV of the OA were significantly decreased in eyes with more severe glaucomatous visual field loss (CRA PSV: 7.6±2.0 cm/s vs 8.3±1.7 cm/s, p=0.04; CRA EDV: 2.24±0.5 cm/s vs 2.55±0.6 cm/s, p<0.007; OA PSV: 29.7±9.9 cm/s vs 32.7±11.5 cm/s, p<0.02). None of the other differences in velocity or resistive index were significant.

Conclusions

Patients with asymmetric glaucomatous visual field loss exhibit asymmetric flow velocities of the CRA and OA. Patients with more severe damage display reduced flow velocities in retrobulbar vessels in POAG.

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Authors and Affiliations

  1. Department of Ophthalmology, RWTH Aachen University, Pauwelsstrasse 30, 52057, Aachen, Germany

    Niklas Plange, Marion Kaup & Andreas Remky

  2. Augenzentrum Alsdorf, Alsdorf, Germany

    Oliver Arend

Authors
  1. Niklas Plange
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  2. Marion Kaup
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  3. Oliver Arend
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  4. Andreas Remky
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Correspondence to Niklas Plange.

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Plange, N., Kaup, M., Arend, O. et al. Asymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucoma. Graefe's Arch Clin Exp Ophthalmo 244, 978–983 (2006). https://doi.org/10.1007/s00417-005-0227-9

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  • DOI: https://doi.org/10.1007/s00417-005-0227-9

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