Biochemical and Biophysical Research Communications
Volume 187, Issue 2, 16 September 1992, Pages 584-589
Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells
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2021, International ImmunopharmacologyCitation Excerpt :Our findings should lead to in vitro investigations oriented towards the search for the levels of enzymatic activities of NOS and arginase and their respective affinities to L-arginine at the level of ECs in the presence of S. aureus. Soluble forms of the adhesion molecules, including sICAM-1 and sE-selectin, are considered as the strong biomarkers of inflammation and ECs activation [71,72]. In our study, both sICAM-1 and sE-selectin were elevated in S. aureus-infected HUVECs, which corroborate various in vitro and in vivo studies showing that S. aureus can induce expression of ICAM-1 and E-selectin [73,74].
Copyright © 1992 Published by Elsevier Inc.