Central serous retinopathy: Variants

doi:10.1016/0039-6257(86)90036-6

Survey of Ophthalmology

Volume 31, Issue 3, November–December 1986, Pages 170-174

https://doi.org/10.1016/0039-6257(86)90036-6 Get rights and content

Abstract

Idiopathic central serous chorioretinopathy (ICSC) is a localized detachment of the sensory retina in the macula which is commonly seen by the general ophthalmologist. However, ICSC with bullous retinal detachment is a rare disease characterized by extensive sensory retinal detachment of the posterior pole and elsewhere. Thus far it has been reported in only nine Caucasian patients in the American literature. Two case reports are presented, one typifying ICSC, the other typifing ICSC with bullous retinal detachment. Although both entities probably share the same pathophysiologic mechanism, they are distinct in terms of diagnostic features and treatment. While ICSC is usually self-limiting and frequently diagnosed by history alone, ICSC with bullous retinal detachment is frequently misdiagnosed and subsequently treated improperly.

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Central serous chorioretinopathy and glucocorticoids
2002, Survey of Ophthalmology
Central serous chorioretinopathy is a relatively common retinal disease characterized by the accumulation of subretinal fluid at the posterior pole of the fundus, creating a circumscribed area of serous retinal detachment. It typically affects young and middle-aged men with no previous medical and family history, and no systemic symptoms or signs. However, it has been noted that central serous chorioretinopathy is associated with different conditions, characterized by exposure to increased levels of endogenous or exogenous glucocorticoids. In fact, central serous chorioretinopathy has been described in patients with endogenous Cushing's syndrome. It is also prevalent in patients with type-A behavior, and following stressful events, and pregnancy probably represents a risk factor for central serous chorioretinopathy; these conditions are characterized by endogenous hypercortisolism. In addition, many cases of central serous chorioretinopathy have been described during or following treatment with glucocorticoids, administrated by any route, for various systemic or ocular conditions. Central serous chorioretinopathy, when related to the exposure to exogenous glucocorticoids, has a less prominent male predilection, presents more often with a chronic or atypical form, and is frequently bilateral. Furthermore, treatment of central serous chorioretinopathy with glucocorticoids was found to exacerbate the clinical picture. Based on these observations it could be suggested that glucocorticoids may be involved in the development of central serous chorioretinopathy, even though the exact pathogenic mechanism remains unclear. Glucocorticoids should not be used in the treatment of central serous chorioretinopathy and central serous chorioretinopathy should be added to the list of ocular complications of glucocorticoids.
Central serous chorioretinopathy in women
1996, Ophthalmology
Background: Central serous Chorioretinopathy is a disorder that typically affects young and middle-aged men. Although extensive information is available pertaining to the clinical features of central serous Chorioretinopathy in men, little is known about this condition in women.
Materials and Methods: The authors reviewed the medical records and photographic files of women who received a diagnosis of central serous Chorioretinopathy. The women were divided into three groups for data analysis: idiopathic, exogenous corticosteroid use, and pregnancy.
Results: Fifty-one women with active central serous Chorioretinopathy were evaluated. The findings in women with idiopathic central serous Chorioretinopathy were similar to those described in men, with the exception that women tend to be older at the time of onset. Central serous Chorioretinopathy in women taking exogenous corticosteroids more likely was characterized by bilateral involvement and subretinal fibrin. Central serous Chorioretinopathy in pregnant women typically developed in the third trimester and resolved spontaneously within 1-2 months after delivery.
Conclusion: Idiopathic central serous Chorioretinopathy is similar in women and men, with the exception that women tend to be older at the time of onset. The finding of exogenous corticosteroid use in a significant number of women in our study provides further support that cortisol may play a role in the development of central serous Chorioretinopathy. The mechanism by which cortisol influences the development of central serous Chorioretinopathy is unclear.
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Central serous retinopathy: Variants

Abstract

Am J Ophthalmol

Am J Ophthalmol

Am J Ophthalmol

Central serous chorioretinopathy with bullous retinal detachment

Ann Ophthalmol