Ciliary neurotrophic factor: A review
References (101)
Neuropoietic cytokines in the hematopoietic fold
Neuron
(1991)- et al.
A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF
Neuron
(1990) - et al.
Ciliary neurotrophic factor supports target-deprived preganglionic sympathetic spinal cord neurons
Neurosci. Lett.
(1989) - et al.
Characterization of a cardiac muscle factor required for the survival of cultured parasympathetic neurons
Neurosci. Lett.
(1980) - et al.
The expression of CNTF message and immunoreactivity in the central and peripheral nervous system of the rat
Devl Brain. Res.
(1992) - et al.
Neurite outgrowth elicited by embryonic chick heart: partial purification of the active factor
Neurosci. Lett.
(1979) - et al.
Purification and characterization of trophic factor embryonic peripheral neurons: comparison with fibroblast growth factors
Neuron.
(1990) - et al.
Proliferation and differentation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor
Neuron
(1989) - et al.
Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo
Neuron
(1992) - et al.
Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS
Neuron
(1992)
The kinetics of interleukin 1 secretion from activated monocytes
J. biol. Chem.
Survival and development in culture of dissociated parasympathetic neurons from ciliary ganglia
Devl. Biol.
Molecular cloning and expression of an IL-6 signal transducer, gp130
Cell
Class 1 heparin binding growth factor promotes the differentiation but not the survival of ciliary neurones in vivo
Devl Brain Res.
Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons
Neuron
CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130
Cell
The alpha component of the CNTF receptor is required for signalling and defines potential CNTF targets in the adult and during development
Neuron
Sequence and structural organization of the human gene encoding ciliary neurotrophic factor
Gene
Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons
Neuron
Cooperative effects of ciliary neurotrophic factor and norepinephrine on tyrosine hydroxylase expression in cultured rat locus coeruleus neurons
Devl Biol.
Leukemia inhibitory factor and ciliary neurotrophic factor regulate expression of muscarinic receptors in cultured sympathetic neurons
Devl Biol.
Effects of ciliary neuronotrophic factor on rat spinal cord neurons in vitro: survival and expression of choline acetyltransferase and low-affinity nerve growth factor receptors
Devl Brain Res.
Purification of adult rat sciatic nerve ciliary neuronotrophic factor
Brain Res.
Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo
Brain Res.
Separation and partial characterization of neuropeptide-inducing factors in heart cell conditioned medium
Neuron
Effects of ciliary neutrophic factor (CNTF) and depolarization on neuropeptide expression in cultured sympathetic neurons
Devl Biol.
Nerve growth activities in rat peripheral nerve
Brain Res.
Decreased synthesis of ciliary neutrophic factor in degenerating peripheral nerves
Brain Res.
Identification of functional receptors for ciliary neurotrophic factor on neuronal cell lines and primary neurons
Neuron
Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component
J. biol. Chem.
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
Cell
High ciliary neuronotrophic specific activity in rat peripheral nerve
Int. J. Devl Neurosci.
Survival effect of ciliary neurotrophic factor (CNTF) on thick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines
J. Neurosci.
Purification of the chick eye ciliary neurotrophic factor
J. Neurochem.
Survival in vitro of motoneurons identified or purified by novel antibody-based methods is selectively enhanced by muscle-derived factors
Development
Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus
Science
Ciliary neurotrophic factor induces sprouting by adult lymnaea neurons in vitro
Soc. Neurosci. Abstr.
Molecular cloning of the interleukin-1β converting enzyme
Science
Ciliary neurotrophic factor prevents retrograde neuronal death in the adults death in the adult central nervous system
The receptor for ciliary neurotrophic factor
Science
Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses
Science
LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor
Science
Comparative screening for ciliary neurotrophic activity in organs of the rat and chicken
J. Neurosci. Res.
Stimulation by tissue explants on nerve fibre outgrowth in culture
Acidic and basic fibroblast growth factors in the nervous system: distribution and differential alteration of levels after injury of central versus peripheral nerve
J. Neurosci.
Molecular cloning and expression of cDNA encoding a murine myeloid leukemia inhibitory factor (LIF)
EMBO J.
The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor
Science
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer gp130
EMBO J.
Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues
J. cell. Biol.
Basic fibroblast growth factor in the hypoglossal system: specific retrograde transport, trophic, and lesion-related responses
J. Neurosci. Res.
Cited by (101)
Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
2022, NeuronCitation Excerpt :Addition of CNTF significantly increased RGC axon regeneration (Figures 2A and 2B). CNTF is a cytokine that acts in part through JAK/STAT signaling (Peterson et al., 2000) and has been shown to be a potent neurotrophic factor in multiple contexts (Fudalej et al., 2021; Richardson, 1994). On its own, CNTF gene therapy primarily acts cell non-autonomously in retinal glial and immune cells (Müller et al., 2007; Xie et al., 2021).
Scope of using hollow fibers as a medium for drug delivery
2022, Fiber and Textile Engineering in Drug Delivery SystemsReduced expression of regeneration associated genes in chronically axotomized facial motoneurons
2015, Experimental NeurologyCitation Excerpt :Trophic support may come from the glial environment of the proximal stump which has been shown to produce trophic factors (Funakoshi et al., 1993; Meyer et al., 1992). Among other factors, BDNF as well as glial derived neurotrophic factor (GDNF) may be derived from the reactive Schwann cells in the neuroma and ciliary neurotrophic factor (CNTF) from intact myelinating Schwann cells (Hammarberg et al., 1996; Meyer et al., 1992; Richardson, 1994; Terenghi, 1999; Boyd and Gordon, 2003). The longer 45–50 mm proximal stump of the sciatic nerve may be a larger source of trophic factors compared to the 12–15 mm long stump of the facial nerve.
Transducible P11-CNTF rescues the learning and memory impairments induced by amyloid-beta peptide in mice
2008, European Journal of PharmacologyNeurotrophic factors
2008, CNS Regeneration