Original ArticlesEffects of peribulbar anesthesia on ocular blood flow in patients undergoing cataract surgery
Section snippets
Patients and methods
The study protocol was approved by the ethics committee of the University of Vienna, School of Medicine, Vienna, Austria and all patients signed an informed consent. In this prospective study, 22 eyes of 22 patients with age-related cataract (age range, 37 to 91 years; mean ± SD, 74.9 ± 15.3 years; 14 women and eight men) were studied. This number of patients was chosen according to the short-term variability of the methods of measurement applied.11 For color Doppler imaging, which has a lower
Results
Baseline mean arterial pressure and pulse rate were 101 ± 13 mm Hg (mean ± SD; confidence interval, 95 to 106 mm Hg) and 71 ± 12 per minute (confidence interval, 66 to 76/min), respectively. Baseline values of ocular hemodynamic measures were as follows: fundus pulsation amplitude, 3.6 ± 1.0 μm (confidence interval, 3.1 to 4.0 μm); mean blood flow velocity and resistive index in the ophthalmic artery, 22.5 ± 6.1 cm per second (confidence interval, 19.6 to 25.4 cm/s) and 0.85 ± 0.05 (confidence
Discussion
The decrease in fundus pulsation amplitude after peribulbar anesthesia reflects a decrease in pulsatile choroidal blood flow. In addition, the decrease in mean blood flow velocity and the increase in resistive index in the central retinal artery indicate a fall in retinal blood flow. This result is in accordance with earlier studies of peribulbar anesthesia–induced effects in ocular hemodynamics.7, 8 By contrast, the lack of effect on mean blood flow velocity and resistive index in the
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