Brief ReportsCox-2 expression in retinoblastoma
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Cited by (30)
Nonsteroidal Anti-inflammatory Drugs in Ophthalmology
2010, Survey of OphthalmologyCitation Excerpt :Use of systemic NSAIDs reduces the incidence of colon cancer by 40–50%, and several epidemiological, clinical, and experimental studies have established NSAIDs as promising cancer chemopreventative agents.126,253,290,318 COX-2 expression is increased in both uveal melanoma and retinoblastoma.61,87,110,162,298 Experimental studies have shown that nepafenac (amfenac) inhibits proliferation of human retinoblastoma cell lines, reduces progression of uveal melanoma, and increases its radiosensitivity.67,86,205
The Expression of Cyclooxygenase 2 in Retinoblastoma: Primary Enucleated Eyes and Enucleation After Conservative Treatment
2006, American Journal of OphthalmologyCitation Excerpt :There seems to be only one short report on the expression of COX-2 in retinoblastoma specimens.8 The authors described a COX-2–positive immunoreaction in the cytoplasm and membrane of the cells of 96% (n = 28) of the retinoblastoma specimens studied leading to the speculation of a possible role of COX-2 in retinoblastoma tumorigenesis.8 Such result is comparable to the findings herein.
Drug repurposing for retinoblastoma: Recent advances
2019, Current Topics in Medicinal ChemistryIbuprofen in the Prevention and Therapy of Cancer
2015, Ibuprofen: Discovery, Development and Therapeutics