Article for CME CreditA comparison of laser photocoagulation with cryotherapy for threshold retinopathy of prematurity at 10 years: part 2. Refractive outcome1 ☆,
Section snippets
Materials and methods
The study population and initial randomization and treatment intervention protocol are described in the preceding report.
Refraction
When considering only patients who had bilateral treatment and favorable outcomes, those treated with laser had a mean SE of −4.48 diopters (D) (standard error of the mean [SEM] = 1.2D), whereas cryotherapy-treated eyes had a mean SE of −7.65 D (SEM = 1.6), (P = 0.019, n = 15 pairs of eyes). However, when all eyes, including fellow eyes of blind or untreated eyes were considered, mean SE for laser-treated eyes was −4.56 D (SEM = 1.1 D) and mean SE for cryotherapy-treated eyes was −7.41 D (SEM =
Discussion
In our previous report,6 we noted that eyes treated with laser photocoagulation had less myopia compared with eyes treated with cryotherapy. The goal of the current phase of this study was to determine the refraction of each of these patients approximately 10 years after treatment, with specific attention to the role of the cornea, AC depth, and axial length of the eye.
After 10 years of follow-up, the laser-treated eyes were significantly less myopic than their cryotherapy-treated counterparts,
Acknowledgements
The authors thank Andrew Smith, PhD, for his extensive statistical assistance with this article.
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Supported by an unrestricted grant from Research to Prevent Blindness, New York, New York, and by a grant from Iridex Corporation, Mountain View, California.
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None of the authors has any financial or proprietary interest in any of the techniques or equipment discussed in this article.