Photorefractive keratectomy for low-to-moderate myopia and astigmatism with a small-beam, tracker-directed excimer laser☆
Section snippets
Patients and methods
Eleven surgeons at six clinical sites in the United States participated in the study, which was conducted under a U.S. Food and Drug Administration-approved Investigational Device Exemption. Enrollment of patients occurred between March 1996 and May 1997. Six hundred seventy-eight eyes of 589 patients were treated with the LADARVision system for correction of spherical myopia between −1 and −10 diopters (D) or for myopic astigmatism between −0.50 and −6 D, in which the maximum spherical
Accountability
Sixty-two eyes were discontinued from the study and not included in the group analysis. Twenty-three eyes were discontinued because of circumstances unrelated to the laser procedure, with an additional eye exited for phototherapeutic keratectomy treatment due to scarring secondary to a corneal ulcer. Follow-up data on these eyes were collected whenever possible (Table 3). The remaining 38 eyes were discontinued for retreatment and are discussed later in this section. Six- and 12-month follow-up
Discussion
These clinical results show the ATC LADARVision excimer laser system is safe and effective for the reduction of low-to-moderate myopia and astigmatism over 1 year. This system produced minimal initial overcorrection with little regression and rapid achievement of refractive stability. Reduction in best-corrected visual acuity of more than 2 lines occurred in only one patient (0.1%) in the entire cohort who was from the low spherical group. Loss of 2 lines or more occurred for 2.2%, 2.5%, and
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Short-term and long-term effects of small incision lenticule extraction (SMILE) on corneal endothelial cells
2015, Contact Lens and Anterior EyeCitation Excerpt :When comparing the preoperative and postoperative ECD, no significant endothelial cell loss was shown at neither 1 day nor 1 year, and the changes were almost negligible. There are numerous studies in which influences of excimer laser-based refractive surgery on corneal endothelial cell loss were tested [15–26], and the annual rate of endothelial cell loss was within the range of physiological age-related endothelial cell loss [27,28]. Recently, endothelial cell loss in patients who underwent femtosecond-assisted refractive surgery was also reported.
Efficacy of two silicone-hydrogel contact lenses for bandage use after photorefractive keratectomy
2013, Contact Lens and Anterior EyeCitation Excerpt :To improve the rate and the quality of epithelial healing following refractive surface procedures, bandage contact lenses (BCLs) are commonly used [3–14], although other approaches, such as occlusive pressure patching [15], have been suggested. This procedure was initially adopted to reduce postoperative pain and decrease dependence on pain medications, as a consequence of the mechanical irritation caused by the eyelids on the abraded cornea [3,4,14,16]. Other studies have demonstrated that a BCL diminishes corneal haze following PRK [17], while it protects the epithelial flap and reduces any risk of flap repositioning in LASEK [8,9,11,13,18].
Comparison of wavefront-guided photorefractive keratectomy and foldable iris-fixated phakic intraocular lens implantation for low to moderate myopia
2011, Journal of Cataract and Refractive SurgeryEfficacy of 2 types of silicone hydrogel bandage contact lenses after photorefractive keratectomy
2009, Journal of Cataract and Refractive SurgeryEffects of lotrafilcon A and omafilcon A bandage contact lenses on visual outcomes after photorefractive keratectomy
2008, Journal of Cataract and Refractive Surgery
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Supported by Autonomous Technologies Corporation, Orlando, Florida.
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Dr. McDonald is a paid consultant for Autonomous Technologies Corporation.