Original articleIncidence and Rates of Visual Field Progression after Longitudinally Measured Optic Disc Change in Glaucoma
Section snippets
Patients
The study participants were patients followed prospectively in an investigation on functional and structural changes in glaucoma with a variety of diagnostic tools. Patients were recruited consecutively from the glaucoma clinics of Capital Health District Authority, Halifax, Nova Scotia, Canada. Inclusion criteria were: (1) clinical diagnosis of open-angle glaucoma with notching or progressive thinning of the neuroretinal rim; (2) baseline visual field mean deviation (MD) between −2 and −10 dB;
Results
There were 81 patients who qualified for the study. The median (interquartile range) age and total follow-up was 59.0 (51.2–69.2) and 11.0 (8.0–12.0) years, respectively. The length of follow-up and number of CSLT and SAP examinations for each protocol in the test and control analysis are shown in Table 1. The mean (± standard deviation) MD at baseline was −5.21±3.43 dB, and at the beginning of the subsequent visual field follow-up in protocols A and B was −5.99±3.98 and −6.14±4.63 dB,
Discussion
New imaging devices for the optic disc have the potential to enhance the clinical care of glaucoma patients. Judging the merit of a new imaging technique in glaucoma typically relies on comparison with an accepted clinical methodology, or reference standard, such as conventional photography or clinical examination. For such comparisons, however, there are a priori assumptions that findings with any new technique should be detected, at the same time or in the future, with the reference standard.
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Manuscript no. 2009-75.
Supported by Grant MOP11357 from the Canadian Institutes of Health Research (BCC).