Original articlePrevalence and Risk Factors for Epiretinal Membranes in a Multi-Ethnic United States Population
Section snippets
Study Population
The Multi-Ethnic Study of Atherosclerosis (MESA) is a prospective cohort study of men and women 45 to 84 years of age without a history of clinical cardiovascular disease sampled from 6 United States communities. Details of the methodology have been described elsewhere.11, 12, 13, 14 In brief, a total of 6814 recruited participants underwent a baseline examination (July 2000 through August 2002). Of these, 6176 returned for a second examination and had retinal photographs taken (August 2002
Participants
The MESA participant characteristics have been presented previously.14, 16 In summary, from 6814 participants recruited at baseline, 6176 participated in the follow-up visit, when retinal images were obtained. Of 6176 participants, 5960 had gradable photographs for ERM. Of the 5960 participants, 39% were white, 27% were black, 22% were Hispanic, and 12% were Chinese. The mean age of participants was 63.2 years (whites, 63.8 years; Chinese, 63.2 years; blacks, 63.0 years; Hispanics, 62.4 years;
Discussion
This study found a nearly 28.9% prevalence of ERM in the MESA population (age-standardized prevalence, 22.7%; 95% confidence interval, 21.5%–23.8%), substantially higher than previously reported in any other study (see Table 4, available at http://aaojournal.org). Other population studies have reported prevalence rates ranging from 6.0% to 11.8% in whites,1, 2, 5 18.0% in Hispanics,4 2.2% to 3.0% in Chinese persons, 4.0% to 5.4% in Japanese persons,6, 9 and 7.9% in Malays.8 To the authors'
References (19)
- et al.
Prevalence and associations of epiretinal membranes: the Blue Mountains Eye Study, Australia
Ophthalmology
(1997) - et al.
Five-year cumulative incidence and progression of epiretinal membranes: the Blue Mountains Eye Study
Ophthalmology
(2003) - et al.
Retinal arteriolar narrowing and left ventricular remodeling: the Multi-Ethnic Study of Atherosclerosis
J Am Coll Cardiol
(2007) - et al.
Prevalence of age-related macular degeneration in 4 racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis
Ophthalmology
(2006) Posterior vitreous detachment and idiopathic preretinal macular gliosis
Am J Ophthalmol
(1986)- et al.
The epidemiology of epiretinal membranes
Trans Am Ophthalmol Soc
(1994) - et al.
Prevalence and associations of epiretinal membranes in Latinos: the Los Angeles Latino Eye Study
Invest Ophthalmol Vis Sci
(2004) - et al.
Prevalence and associations of epiretinal membranes in the Visual Impairment Project
Am J Ophthalmol
(2005) - et al.
Prevalence and risk factors for epiretinal membranes in a Japanese population: the Hisayama study
Graefes Arch Clin Exp Ophthalmol
(2003)
Cited by (181)
Evaluation of Foveal Cone and Müller Cells in Epiretinal Membrane using Adaptive Optics OCT
2024, Ophthalmology ScienceIdiopathic epiretinal membranes: postoperative changes in morphology
2023, Canadian Journal of OphthalmologyDeep learning-based postoperative visual acuity prediction in idiopathic epiretinal membrane
2023, BMC Ophthalmology
Manuscript no. 2009-1402.
Supported by the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (grant nos.: N01-HC-95159 through N01-HC-95165 and N01-HC-95169); the National Institutes of Health, Bethesda, Maryland (grant no.: HL69979-03 [RK and TYW); and the National Eye Institute, National Institutes of Health, Bethesda, Maryland (grant no.: Z01EY000403 [MFC]). The funding source had no role in the design or conduct of this research.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.