Original articleEnhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus in 104 Cases
Section snippets
Patients and Methods
This was a retrospective, observational study, approved by the institutional review board, designed to describe the characteristics of choroidal nevus (thickness ≤3 mm) using the EDI OCT technique. In addition to complete eye examination with dilated pupil, digital fundus photography, fundus autofluorescence, and ultrasonography, all patients diagnosed with choroidal nevus over a 6-month period from August 1, 2010, to January 31, 2011, at the Ocular Oncology Service, Wills Eye Institute,
Results
Of 104 choroidal nevi in 103 patients who underwent EDI OCT imaging over a 6-month period, the quality of the image was judged to be optimal in 51 (49%) and suboptimal in 53 (51%). The clinical factors responsible for image quality (optimal, suboptimal) were investigated statistically using the Student's t test and the chi-square test and are summarized in Table 1. Older age, female gender, extramacular location, greater distance of the margin of the nevus from the foveola and from the disc,
Discussion
Optical coherence tomography is a valuable tool for assessment of the status of the overlying retina and RPE with choroidal tumors.11 Previous studies using time-domain (TD) OCT for evaluation of choroidal nevus have reported findings limited to the retina with little choroidal detail resulting from poor resolution of TD OCT for choroidal structures.12, 13 Schaudig et al14 recognized these limitations and suggested that OCT was of little value in the differential diagnosis of choroidal tumors.
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Manuscript no. 2011-1003.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by Eye Tumor Research Foundation, Philadelphia, Pennsylvania (CLS, JAS). The funders had no role in the design and conduct of the study; in the collection, analysis, or interpretation of the data; or in the preparation, review, or approval of the manuscript. Carol L. Shields, MD, has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.