Abstract
Purpose:
To report a case of fungal keratitis resulting after laser in situ keratomileusis (LASIK).
Methods:
A 38-year-old white man in good health developed a corneal infiltrate with laboratory confirmation of fungal keratitis after LASIK. Corneal scrapings were taken. Silver stain was positive for hyphae. Culture was positive for Curvularia sp. The patient was started on intensive natamycin 5% and amphotericin 0.15% topical therapy.
Results:
The patient's keratitis was successfully treated with intensive antifungal therapy.
Conclusions:
Infectious keratitis is a rare but a serious potential complication after LASIK. To our knowledge, no previous case of fungal keratitis after LASIK has been reported. This case emphasizes the importance of surveillance for infection after LASIK.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Amphotericin B / administration & dosage
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Amphotericin B / therapeutic use
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Antifungal Agents / administration & dosage
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Antifungal Agents / therapeutic use
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Cornea / microbiology
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Cornea / pathology
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Corneal Ulcer / drug therapy
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Corneal Ulcer / microbiology*
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Corneal Ulcer / pathology
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Drug Therapy, Combination
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Eye Infections, Fungal / drug therapy
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Eye Infections, Fungal / etiology*
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Eye Infections, Fungal / pathology
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Humans
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Keratomileusis, Laser In Situ / adverse effects*
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Male
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Mitosporic Fungi / isolation & purification*
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Mycoses / drug therapy
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Mycoses / etiology*
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Mycoses / pathology
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Myopia / surgery
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Natamycin / administration & dosage
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Natamycin / therapeutic use
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Ophthalmic Solutions
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Visual Acuity
Substances
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Antifungal Agents
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Ophthalmic Solutions
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Amphotericin B
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Natamycin