Decrease in tear secretion and corneal sensitivity after laser in situ keratomileusis

Cornea. 2001 Jan;20(1):30-2. doi: 10.1097/00003226-200101000-00005.

Abstract

Purpose: To evaluate tear secretion and corneal sensitivity after laser in situ keratomileusis (LASIK) for the correction of myopia.

Methods: In a prospective study, 48 consecutive eyes (24 patients) underwent LASIK to correct myopia ranging from -3.5 to -12.25 diopters. Tear secretion tested by the tear function index and corneal sensitivity tested using the Cochet-Bonnet esthesiometer were evaluated preoperatively and 1 week and 1, 3, 6, and 9 months postoperatively.

Results: Tear secretion and corneal sensitivity after LASIK were reduced during the first 3 months after surgery (p<0.001). Tear secretion returned to its preoperative values only after 9 months. Tear secretion and corneal sensitivity were more depressed in long-term contact lens wearers preoperatively and 6 months after surgery (p<0.05).

Conclusion: In the correction of myopia, tear secretion was depressed after LASIK during the first 6 months after surgery.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Blinking
  • Cornea / innervation
  • Cornea / physiopathology*
  • Cornea / surgery
  • Dry Eye Syndromes / etiology
  • Dry Eye Syndromes / metabolism
  • Dry Eye Syndromes / physiopathology
  • Dry Eye Syndromes / prevention & control
  • Female
  • Humans
  • Keratomileusis, Laser In Situ* / adverse effects
  • Male
  • Middle Aged
  • Myopia / surgery
  • Ophthalmic Solutions / administration & dosage
  • Postoperative Period
  • Prospective Studies
  • Recovery of Function
  • Sensory Thresholds
  • Tears / metabolism*

Substances

  • Ophthalmic Solutions