Abstract
The healing process after glaucoma filtration is the main determinant of surgical failure and, even more important, the final intraocular pressure. The ability to fully control wound healing may ultimately give us the ability to set the intraocular pressure in the low teens for all patients undergoing glaucoma filtration surgery. The authors review the changes in how to use antimetabolites to improve safety, and many of the exciting new areas of progress, including growth factor neutralization and future molecular therapies to control wound healing.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Antimetabolites / administration & dosage
-
Apoptosis / drug effects
-
Cell Division / drug effects
-
Conjunctiva / pathology
-
Extracellular Matrix / drug effects
-
Extracellular Matrix / pathology
-
Filtering Surgery*
-
Glaucoma / surgery*
-
Humans
-
Immunosuppressive Agents / administration & dosage
-
Intraocular Pressure
-
Ophthalmic Solutions
-
Postoperative Period
-
Wound Healing* / drug effects
-
Wound Healing* / physiology
Substances
-
Antimetabolites
-
Immunosuppressive Agents
-
Ophthalmic Solutions