Peters' anomaly and combination with other malformations (series of 16 patients)

Ophthalmic Paediatr Genet. 1992 Jun;13(2):131-5. doi: 10.3109/13816819209087613.

Abstract

A series of 15 patients with Peters' anomaly observed from 1987-1991 and a patient showing Wolf-Hirschhorn syndrome were studied retrospectively. Combined ocular anomalies were: microphthalmos (9x), myopia (4x), aniridia (2x), cataract (2x). Five of the patients had combined general anomalies: mental retardation, deafness, cardiac malformation (ASD II), and luxatio coxae. In two of them chromosomal anomalies were found: 4p minus syndrome, mosaic trisomy 9. After comparison of these data with those known from the literature the author confirms that Peters' anomaly is a morphologic finding rather than a distinct entity. Treatment depends on individual histopathologic findings and on the psychophysical development of the child.

MeSH terms

  • Abnormalities, Multiple / genetics
  • Adult
  • Anterior Eye Segment / abnormalities*
  • Child
  • Child, Preschool
  • Corneal Opacity / complications
  • Eye Abnormalities / complications
  • Eye Abnormalities / genetics
  • Humans
  • Infant
  • Retrospective Studies