A method of preparing antigen-free cancellous bone for use as an orbital implant is described together with the surgical technique for its use in enucleation. The results of 52 patients with follow-up spanning 10 years is reported. In the first four years, five implants had to be removed, all due to infection following breakdown of Tenon's capsule in the early postoperative period. However, with more careful closure of Tenon's capsule, there have been no extrusions during the last six years.