Posterior capsular opacification and intraocular lens decentration. Part II: Experimental findings on a prototype circular intraocular lens design

M R Tetz; D J O'Morchoe; T D Gwin; T H Wilbrandt; K D Solomon; S O Hansen; D J Apple

doi:10.1016/s0886-3350(88)80028-2

Posterior capsular opacification and intraocular lens decentration. Part II: Experimental findings on a prototype circular intraocular lens design

J Cataract Refract Surg. 1988 Nov;14(6):614-23. doi: 10.1016/s0886-3350(88)80028-2.

Authors

M R Tetz¹, D J O'Morchoe, T D Gwin, T H Wilbrandt, K D Solomon, S O Hansen, D J Apple

Affiliation

¹ Department of Ophthalmology, University of Utah Health Sciences Center, Salt Lake City.

PMID: 3230514
DOI: 10.1016/s0886-3350(88)80028-2

Abstract

In a prospective randomized study, 25 New Zealand white rabbit eyes were implanted with four intraocular lens (IOL) designs. These included a one-piece modified J-loop IOL, a three-piece modified J-loop IOL, a rigid disc IOL, and an experimental compressible disc (CD) IOL. The CD IOL revealed the lowest mean posterior capsular opacification (PCO) of all IOLs tested (P less than .01). With all lenses tested, a positive correlation between PCO and decentration was found (R = 0.55, P less than .05). These results suggest that because of its design features (i.e., one-piece construction, biconvex optic, posterior angulation of the fixation element), the CD lens produces a mechanical barrier against lens epithelial cell migration and reduces the incidence of PCO.

MeSH terms

Animals
Cataract Extraction
Equipment Design
Evaluation Studies as Topic
Lens Capsule, Crystalline / surgery
Lenses, Intraocular / adverse effects*
Lenses, Intraocular / methods
Prospective Studies
Rabbits