Abstract
We used wide-field color specular microscopy of the human corneal surface to study the morphologic changes that occur under extended-wear contact lenses. There was a shift in the frequency distribution of surface cells by size to larger cells, suggesting a prolonged residence time on the ocular surface. Other abnormalities included retained desiccated mucin, coarse mucus plaques, and palisading of cells.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Aged
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Aphakia, Postcataract / therapy
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Contact Lenses, Extended-Wear / adverse effects*
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Contact Lenses, Hydrophilic / adverse effects*
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Cornea / pathology*
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Cornea / ultrastructure
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Epithelium / pathology
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Epithelium / ultrastructure
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Humans
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Microscopy, Electron, Scanning
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Middle Aged
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Myopia / therapy