Eight patients with superior limbic keratoconjunctivitis (SLK) were successfully treated with the use of pressure patching and therapeutic soft contact lenses. In two patients, pressure patching alone was used to eliminate both the signs and symptoms of SLK. Therapeutic soft contact lenses were used after pressure patching in the other six patients to prevent recurrences of SLK. Our results suggest that eliminating the mechanical effect of the lid on the globe by pressure patching and then protecting the superior corneal limbus and adjacent bulbar conjunctiva by soft contact lenses may provide an alternative to silver nitrate applications in the treatment of SLK.