The clinicopathologic features of photocoagulation lesion expansion after two separate sessions of krypton red laser for choroidal neovascularization (CNV) in an eye with age-related macular degeneration are presented. The area of expansion is characterized by retinal pigment epithelial atrophy and loss of the photoreceptor cell layer. A thin margin of retinal pigment epithelium hypopigmentation and variable photoreceptor cell layer degeneration also borders the lesion in some areas.