Periocular anesthesia is a proven alternative to retrobulbar anesthesia. A prospective evaluation of 1,000 cases was done to study the advantages of single point, low volume periocular anesthesia. This method is efficacious and has an excellent safety profile. The small needle length and the low volume of injected anesthetic enhance the safety. Supplemental anesthesia was needed in only 0.2% of cases. Chemosis was noted in 12.7%. In no case did surgery have to be postponed because of anesthesia-related complications. We believe this method is superior to other multipoint high volume methods of periocular anesthesia.