Electroretinography of central retinal vein occlusion under scotopic and photopic conditions: what to measure?

Acta Ophthalmol Scand. 1997 Feb;75(1):48-53. doi: 10.1111/j.1600-0420.1997.tb00249.x.

Abstract

Introduction: In the management of cases of central retinal vein occlusion it is important to identify those patients who will develop the complication of iris neovascularisation. Electroretinography is of proven use in this role but there is some confusion about which parameters to measure and at what stimulus intensities.

Methods: A variety of ERG parameters in scotopic and photopic conditions were tested by ROC analysis for the prediction of the development of this complication in 39 patients with CRVO.

Results: The results indicated that a single flash and measurement of the b/a ratio under photopic conditions is as effective in this aim as measuring multiple parameters.

Conclusion: A simplified and shortened protocol could be used in the examination of this condition thereby making the application of ERG more practical in the clinical setting.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Ocular / physiology*
  • Adult
  • Aged
  • Aged, 80 and over
  • Dark Adaptation / physiology
  • Electroretinography*
  • Female
  • Humans
  • Iris / blood supply
  • Light
  • Male
  • Middle Aged
  • Neovascularization, Pathologic / diagnosis
  • Neovascularization, Pathologic / etiology
  • Neovascularization, Pathologic / physiopathology
  • ROC Curve
  • Retinal Vein / physiopathology
  • Retinal Vein Occlusion / complications
  • Retinal Vein Occlusion / diagnosis
  • Retinal Vein Occlusion / physiopathology*
  • Scattering, Radiation