Recurrent nodular scleritis associated with varicella zoster virus

C Livir-Rallatos; Y El-Shabrawi; P Zatirakis; P E Pellett; F R Stamey; C S Foster

doi:10.1016/s0002-9394(98)00120-2

Recurrent nodular scleritis associated with varicella zoster virus

Am J Ophthalmol. 1998 Oct;126(4):594-7. doi: 10.1016/s0002-9394(98)00120-2.

Authors

C Livir-Rallatos¹, Y El-Shabrawi, P Zatirakis, P E Pellett, F R Stamey, C S Foster

Affiliation

¹ Uveitis and Immunology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.

PMID: 9780109
DOI: 10.1016/s0002-9394(98)00120-2

Abstract

Purpose: To describe a case of recurrent nodular scleritis that was apparently caused by reactivation of a varicella zoster virus infection.

Methods: Case report. Immunohistochemistry and polymerase chain reaction were used to detect viral antigen and DNA in the biopsy specimen of inflamed sclera of a patient with a history of recurrent nodular scleritis.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

2-Aminopurine / analogs & derivatives
2-Aminopurine / therapeutic use
Antigens, Viral / analysis
Antiviral Agents / therapeutic use
DNA Primers / chemistry
DNA, Viral / analysis
Famciclovir
Female
Fluorescent Antibody Technique, Indirect
Herpes Zoster Ophthalmicus / diagnosis
Herpes Zoster Ophthalmicus / drug therapy
Herpes Zoster Ophthalmicus / virology*
Herpesvirus 3, Human / genetics
Herpesvirus 3, Human / growth & development*
Herpesvirus 3, Human / immunology
Humans
Middle Aged
Polymerase Chain Reaction
Recurrence
Sclera / pathology
Sclera / virology
Scleritis / diagnosis
Scleritis / drug therapy
Scleritis / virology*
Virus Activation

Substances

Antigens, Viral
Antiviral Agents
DNA Primers
DNA, Viral
2-Aminopurine
Famciclovir