Ocular allergy: recognizing and diagnosing hypersensitivity disorders of the ocular surface
A Leonardi, E Bogacka, JL Fauquert, ML Kowalski… - Allergy, 2012 - Wiley Online Library
Ocular allergy includes several clinically different conditions that can be considered as
hypersensitivity disorders of the ocular surface. The classification of these conditions is …
hypersensitivity disorders of the ocular surface. The classification of these conditions is …
Vernal keratoconjunctivitis: pathogenesis and treatment
A Leonardi - Progress in retinal and eye research, 2002 - Elsevier
Vernal keratoconjunctivitis (VKC) is a recurrent or chronic ocular allergic disease that affects
mostly children and young adults living in warm climates worldwide. Understanding and …
mostly children and young adults living in warm climates worldwide. Understanding and …
[HTML][HTML] Global observing needs in the deep ocean
The deep ocean below 200 m water depth is the least observed, but largest habitat on our
planet by volume and area. Over 150 years of exploration has revealed that this dynamic …
planet by volume and area. Over 150 years of exploration has revealed that this dynamic …
Requirement for NF-κB in osteoclast and B-cell development
…, EW Shores, KD Brown, A Leonardi… - Genes & …, 1997 - genesdev.cshlp.org
NF-κB is a family of related, dimeric transcription factors that are readily activated in cells by
signals associated with stress or pathogens. These factors are critical to host defense, as …
signals associated with stress or pathogens. These factors are critical to host defense, as …
Mice deficient in nuclear factor (NF)-κB/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
p52 is a subunit of nuclear factor (NF)-κB transcription factors, most closely related to p50.
Previously, we have shown that p52, but not p50 homodimers can form transactivating …
Previously, we have shown that p52, but not p50 homodimers can form transactivating …
Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural …
SH Ahmed, LL Clark, WR Pennington, CS Webb… - Circulation, 2006 - Am Heart Assoc
Background—Chronic hypertension may cause left ventricular (LV) remodeling, alterations
in cardiac function, and the development of chronic heart failure (CHF). Changes in the …
in cardiac function, and the development of chronic heart failure (CHF). Changes in the …
Combining quantitative trait loci analysis and an ecophysiological model to analyze the genetic variability of the responses of maize leaf growth to temperature and …
M Reymond, B Muller, A Leonardi… - Plant …, 2003 - academic.oup.com
Ecophysiological models predict quantitative traits of one genotype in any environment,
whereas quantitative trait locus (QTL) models predict the contribution of alleles to …
whereas quantitative trait locus (QTL) models predict the contribution of alleles to …
A CMOS chip for individual cell manipulation and detection
…, G Medoro, L Altomare, A Leonardi… - IEEE Journal of Solid …, 2003 - ieeexplore.ieee.org
Manipulation of populations of living cells on an individual basis is essential for the
investigation of complex interactions among cells. We present a new approach to the …
investigation of complex interactions among cells. We present a new approach to the …
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics
…, SP Kerkar, RD Michalek, T Upham, A Leonardi… - Cancer research, 2015 - AACR
Adoptive cell therapy (ACT) using autologous tumor-infiltrating lymphocytes (TIL) results in
complete regression of advanced cancer in some patients, but the efficacy of this potentially …
complete regression of advanced cancer in some patients, but the efficacy of this potentially …
[HTML][HTML] IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors
SP Kerkar, RS Goldszmid, P Muranski… - The Journal of …, 2011 - Am Soc Clin Investig
Solid tumors are complex masses with a local microenvironment, or stroma, that supports
tumor growth and progression. Among the diverse tumor-supporting stromal cells is a …
tumor growth and progression. Among the diverse tumor-supporting stromal cells is a …