Leukocyte-mediated endothelial cell injury and death in the diabetic retina

AM Joussen, T Murata, A Tsujikawa, B Kirchhof… - The American journal of …, 2001 - Elsevier
Endothelial cell death is a hallmark of diabetic retinopathy. Its occurrence is required for the
formation of acellular (devitalized) capillaries, lesions that produce irreversible retinal …

[HTML][HTML] Macular choroidal thickness and volume in normal subjects measured by swept-source optical coherence tomography

M Hirata, A Tsujikawa, A Matsumoto… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: To study the choroidal thickness in healthy subjects by swept-source optical
coherence tomography (SS-OCT) at longer wavelength. Methods.: The macular area of 31 …

[HTML][HTML] Characteristics of pachychoroid diseases and age-related macular degeneration: multimodal imaging and genetic backgrounds

K Yamashiro, Y Hosoda, M Miyake, S Ooto… - Journal of clinical …, 2020 - mdpi.com
The emergence of pachychoroid disease is changing the concept of age-related macular
degeneration (AMD). The concept of pachychoroid diseases was developed through clinical …

Prevalence and pattern of geographic atrophy in Asia: the Asian Eye Epidemiology Consortium

TH Rim, R Kawasaki, YC Tham, SW Kang… - Ophthalmology, 2020 - Elsevier
Purpose Although there have been many population-based studies of age-related macular
degeneration (AMD), only limited information is available in Asia on the epidemiology of …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Assessment of macular choroidal thickness by optical coherence tomography and angiographic changes in central serous chorioretinopathy

P Jirarattanasopa, S Ooto, A Tsujikawa, K Yamashiro… - Ophthalmology, 2012 - Elsevier
OBJECTIVE: To investigate the relationship between macular choroidal thickness measured
by high-penetrating swept-source optical coherence tomography (SS-OCT) and …

[HTML][HTML] Relationship between pachychoroid and polypoidal choroidal vasculopathy

K Yamashiro, Y Yanagi, H Koizumi… - Journal of Clinical …, 2022 - mdpi.com
Previous clinical studies have suggested that pachychoroid can induce macular
neovascularization (MNV) to develop pachychoroid neovasculopathy (PNV) and that PNV …

Suppression of diabetic retinopathy with angiopoietin-1

AM Joussen, V Poulaki, A Tsujikawa, W Qin… - The American journal of …, 2002 - Elsevier
Diabetic retinopathy remains a leading cause of irreversible blindness. A critical early
pathology in the disease is the adhesion of leukocytes to the retinal vasculature, a process …

In vivo demonstration of increased leukocyte entrapment in retinal microcirculation of diabetic rats.

K Miyamoto, N Hiroshiba… - … & visual science, 1998 - iovs.arvojournals.org
PURPOSE: Leukocytes have been reported to be less deformable and more activated in
diabetes. It has also been suggested that they cause microvascular occlusions that may …

Polypoidal choroidal vasculopathy with choroidal vascular hyperpermeability

M Sasahara, A Tsujikawa, K Musashi, N Gotoh… - American journal of …, 2006 - Elsevier
PURPOSE: To describe the incidence and clinical characteristics of polypoidal choroidal
vasculopathy (PCV) associated with choroidal vascular hyperpermeability. DESIGN …