User profiles for "author:D Khoury"

David Khoury

- Verified email at unsw.edu.au - Cited by 8773

Dalia El Khoury

- Verified email at uoguelph.ca - Cited by 2233

[HTML][HTML] Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection

D Cromer, JA Juno, D Khoury, A Reynaldi… - Nature Reviews …, 2021 - nature.com
Immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
central to long-term control of the current pandemic. Despite our rapidly advancing …

[HTML][HTML] Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?

SJ Kent, DS Khoury, A Reynaldi, JA Juno… - Nature Reviews …, 2022 - nature.com
The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …

[HTML][HTML] Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract

A Jahan-Mihan, BL Luhovyy, DE Khoury, GH Anderson - Nutrients, 2011 - mdpi.com
Dietary proteins elicit a wide range of nutritional and biological functions. Beyond their
nutritional role as the source of amino acids for protein synthesis, they are instrumental in …

[HTML][HTML] Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

S Cele, L Jackson, DS Khoury, K Khan, T Moyo-Gwete… - Nature, 2022 - nature.com
The emergence of the SARS-CoV-2 variant of concern Omicron (Pango lineage B. 1.1. 529),
first identified in Botswana and South Africa, may compromise vaccine effectiveness and …

[HTML][HTML] Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

DS Khoury, D Cromer, A Reynaldi, TE Schlub… - Nature medicine, 2021 - nature.com
Predictive models of immune protection from COVID-19 are urgently needed to identify
correlates of protection to assist in the future deployment of vaccines. To address this, we …

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

RR Goel, MM Painter, SA Apostolidis, D Mathew… - Science, 2021 - science.org
INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA
vaccines are highly effective at preventing infection and especially severe disease …

[HTML][HTML] Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis

D Cromer, M Steain, A Reynaldi, TE Schlub… - The Lancet …, 2022 - thelancet.com
Summary Background Several SARS-CoV-2 variants of concern have been identified that
partly escape serum neutralisation elicited by current vaccines. Studies have also shown …

[HTML][HTML] SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection

S Cele, L Jackson, DS Khoury, K Khan, T Moyo-Gwete… - MedRxiv, 2021 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 Omicron, first identified in Botswana and South Africa, may
compromise vaccine effectiveness and the ability of antibodies triggered by previous …

[HTML][HTML] Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

AK Wheatley, JA Juno, JJ Wang, KJ Selva… - Nature …, 2021 - nature.com
The durability of infection-induced SARS-CoV-2 immunity has major implications for
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …

[HTML][HTML] Suppression of canonical Wnt/β-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy

E Garcia-Gras, R Lombardi… - The Journal of …, 2006 - Am Soc Clin Investig
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is a genetic disease
caused by mutations in desmosomal proteins. The phenotypic hallmark of ARVC is …