Assessment of epidermal nerve fibers: a new diagnostic and predictive tool for peripheral neuropathies

GJ Ebenezer, P Hauer, C Gibbons… - … of Neuropathology & …, 2007 - academic.oup.com
Today, skin biopsies can play an important role in the diagnosis of peripheral nerve
disorders and have yielded another diagnostic tool for the neurologist. One of the commonly …

Mechanisms of nerve injury in leprosy

DM Scollard, RW Truman, GJ Ebenezer - Clinics in dermatology, 2015 - Elsevier
All patients with leprosy have some degree of nerve involvement. Perineural inflammation is
the histopathologic hallmark of leprosy, and this localization may reflect a vascular route of …

[HTML][HTML] Treatment and evaluation advances in leprosy neuropathy

GJ Ebenezer, DM Scollard - Neurotherapeutics, 2021 - Elsevier
Neuropathy and related disabilities are the major medical consequences of leprosy, which
remains a global medical concern. Despite major advances in understanding the …

Denervation of skin in neuropathies: the sequence of axonal and Schwann cell changes in skin biopsies

GJ Ebenezer, JC McArthur, D Thomas, B Murinson… - Brain, 2007 - academic.oup.com
We compared the pathological changes in cutaneous axons and Schwann cells of
individuals with nerve transection to the changes in patients with chronic neuropathies …

Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy

L Zhou, DW Kitch, SR Evans, P Hauer, S Raman… - Neurology, 2007 - AAN Enterprises
Objective: To demonstrate the relationship between epidermal nerve fiber density (ENFD) in
the leg and the phenotype of HIV-associated distal sensory polyneuropathy (HIV-DSP) in a …

Antiretroviral use and other risks for HIV-associated neuropathies in an international cohort

CL Cherry, RL Skolasky, L Lal, J Creighton, P Hauer… - Neurology, 2006 - AAN Enterprises
Objective: To explore the association between specific nucleoside reverse transcriptase
inhibitors and sensory neuropathies (SNs) and define the modifying roles of hepatitis C …

Impaired neurovascular repair in subjects with diabetes following experimental intracutaneous axotomy

GJ Ebenezer, R O'Donnell, P Hauer, NP Cimino… - Brain, 2011 - academic.oup.com
Diabetic complications and vascular disease are closely intertwined. Diabetes mellitus is a
well-established risk factor for both large and small vessel vascular changes, and …

Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy

GJ Ebenezer, Y Liu, DP Judge… - Annals of …, 2017 - Wiley Online Library
Objective To determine the utility of skin biopsies as a biomarker of disease severity in
subjects with amyloid neuropathy. Methods Five groups of patients were studied:(1) …

[HTML][HTML] LepVax, a defined subunit vaccine that provides effective pre-exposure and post-exposure prophylaxis of M. leprae infection

MS Duthie, MT Pena, GJ Ebenezer, TP Gillis… - npj Vaccines, 2018 - nature.com
Sustained elimination of leprosy as a global health concern likely requires a vaccine. The
current standard, BCG, confers only partial protection and precipitates paucibacillary (PB) …

The armadillo as a model for peripheral neuropathy in leprosy

RW Truman, GJ Ebenezer, MT Pena, R Sharma… - ILAR …, 2014 - academic.oup.com
Leprosy (also known as Hansen's Disease) is a chronic infectious disease caused by
Mycobacterium leprae that primarily targets the peripheral nervous system; skin, muscle …