Depth-resolved model-based reconstruction of attenuation coefficients in optical coherence tomography
KA Vermeer, J Mo, JJA Weda, HG Lemij… - Biomedical optics …, 2014 - opg.optica.org
We present a method, based on a single scattering model, to calculate the attenuation
coefficient of each pixel in optical coherence tomography (OCT) depth profiles. Numerical …
coefficient of each pixel in optical coherence tomography (OCT) depth profiles. Numerical …
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma, and
variability in IOP might herald glaucomatous development or progression. We report the …
variability in IOP might herald glaucomatous development or progression. We report the …
[HTML][HTML] A genome-wide association study of optic disc parameters
WD Ramdas, LME van Koolwijk, MK Ikram… - PLoS …, 2010 - journals.plos.org
The optic nerve head is involved in many ophthalmic disorders, including common diseases
such as myopia and open-angle glaucoma. Two of the most important parameters are the …
such as myopia and open-angle glaucoma. Two of the most important parameters are the …
[HTML][HTML] Common genetic determinants of intraocular pressure and primary open-angle glaucoma
LME van Koolwijk, WD Ramdas, MK Ikram… - PLoS …, 2012 - journals.plos.org
Intraocular pressure (IOP) is a highly heritable risk factor for primary open-angle glaucoma
and is the only target for current glaucoma therapy. The genetic factors which determine IOP …
and is the only target for current glaucoma therapy. The genetic factors which determine IOP …
A model based method for retinal blood vessel detection
KA Vermeer, FM Vos, HG Lemij… - Computers in biology and …, 2004 - Elsevier
Retinal blood vessels are important structures in ophthalmological images. Many detection
methods are available, but the results are not always satisfactory. In this paper, we present a …
methods are available, but the results are not always satisfactory. In this paper, we present a …
Common genetic variants associated with open-angle glaucoma
WD Ramdas, LME van Koolwijk… - Human molecular …, 2011 - academic.oup.com
Open-angle glaucoma (glaucoma) is a major eye disorder characterized by optic disc
pathology. Recent genome-wide association studies identified new loci associated with …
pathology. Recent genome-wide association studies identified new loci associated with …
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
H Springelkamp, AI Iglesias, A Mishra… - Human molecular …, 2017 - academic.oup.com
Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …
Meta‐analysis of genome‐wide association studies identifies novel loci associated with optic disc morphology
Primary open‐angle glaucoma is the most common optic neuropathy and an important
cause of irreversible blindness worldwide. The optic nerve head or optic disc is divided in …
cause of irreversible blindness worldwide. The optic nerve head or optic disc is divided in …
Automated segmentation by pixel classification of retinal layers in ophthalmic OCT images
KA Vermeer, J Van der Schoot, HG Lemij… - Biomedical optics …, 2011 - opg.optica.org
Current OCT devices provide three-dimensional (3D) in-vivo images of the human retina.
The resulting very large data sets are difficult to manually assess. Automated segmentation …
The resulting very large data sets are difficult to manually assess. Automated segmentation …
Clinical assessment of stereoscopic optic disc photographs for glaucoma: the European Optic Disc Assessment Trial
NJ Reus, HG Lemij, DF Garway-Heath, PJ Airaksinen… - Ophthalmology, 2010 - Elsevier
PURPOSE: To determine the diagnostic accuracy of judging optic disc photographs for
glaucoma by ophthalmologists. DESIGN: Evaluation of diagnostic test and technology …
glaucoma by ophthalmologists. DESIGN: Evaluation of diagnostic test and technology …