Whole-population vision screening in children aged 4–5 years to detect amblyopia

AL Solebo, PM Cumberland, JS Rahi - The Lancet, 2015 - thelancet.com
Amblyopia is a neurodevelopmental disorder that affects at least 2% of most populations
and can lead to permanently reduced vision if not detected and treated within a specific …

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

VJM Verhoeven, PG Hysi, R Wojciechowski, Q Fan… - Nature …, 2013 - nature.com
Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …

[HTML][HTML] Genome-wide association studies of refractive error and myopia, lessons learned, and implications for the future

PG Hysi, R Wojciechowski, JS Rahi… - … & visual science, 2014 - tvst.arvojournals.org
The investigation of the genetic basis of refractive error and myopia entered a new stage
with the introduction of genome-wide association studies (GWAS). Multiple GWAS on many …

Severe visual impairment and blindness in children in the UK

JS Rahi, N Cable - The Lancet, 2003 - thelancet.com
Background Prevention of visual impairment and blindness in childhood is an international
priority. However, many countries do not have contemporary information about incidence …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Risk, causes, and outcomes of visual impairment after loss of vision in the non-amblyopic eye: a population-based study

JS Rahi, S Logan, C Timms, I Russell-Eggitt, D Taylor - The Lancet, 2002 - thelancet.com
Background Screening for amblyopia in early childhood is done in many countries to ensure
that affected children are detected and treated within the critical period, and achieve a level …

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25

PG Hysi, TL Young, DA Mackey, T Andrew… - Nature …, 2010 - nature.com
Myopia and hyperopia are at opposite ends of the continuum of refraction, the measure of
the eye′ s ability to focus light, which is an important cause of visual impairment (when …

Childhood blindness in India: causes in 1318 blind school students in nine states

JS Rahi, S Sripathi, CE Gilbert, A Foster - Eye, 1995 - nature.com
It is estimated that at least 200 000 children in India have severe visual impairment or
blindness and approximately 15 000 are in schools for the blind. Although this represents a …

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

PG Hysi, H Choquet, AP Khawaja, R Wojciechowski… - Nature …, 2020 - nature.com
Refractive errors, in particular myopia, are a leading cause of morbidity and disability
worldwide. Genetic investigation can improve understanding of the molecular mechanisms …

[HTML][HTML] Measuring and interpreting the incidence of congenital ocular anomalies: lessons from a national study of congenital cataract in the UK

JS Rahi, C Dezateaux - Investigative ophthalmology & visual …, 2001 - iovs.arvojournals.org
purpose. Prevention of visual impairment due to congenital cataract is an international
priority. Estimates of incidence are required for implementation and assessment of …