A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

C Bertolotto, F Lesueur, S Giuliano, T Strub, M De Lichy… - Nature, 2011 - nature.com
So far, no common environmental and/or phenotypic factor has been associated with
melanoma and renal cell carcinoma (RCC). The known risk factors for melanoma include …

Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice

E Tartour, F Fossiez, I Joyeux, A Galinha, A Gey… - Cancer research, 1999 - AACR
Interleukin (IL) 17 is a proinflammatory cytokine secreted mainly by activated human
memory CD4 T cells that induces IL-6, IL-8, and nitric oxide. Because IL-6 and IL-8 have …

PRCC-TFE3 renal carcinomas: morphologic, immunohistochemical, ultrastructural, and molecular analysis of an entity associated with the t (X; 1)(p11. 2; q21)

P Argani, CR Antonescu, J Couturier… - The American journal …, 2002 - journals.lww.com
The reappraisal of genetically defined subsets of renal tumors can help to highlight the key
pathologic features of specific neoplastic entities. We report the morphologic …

[PDF][PDF] Overall genomic pattern is a predictor of outcome in neuroblastoma

I Janoueix-Lerosey, G Schleiermacher… - Journal of clinical …, 2009 - researchgate.net
Overall Genomic Pattern Is a Predictor of Outcome in Neuroblastoma Page 1 Overall Genomic
Pattern Is a Predictor of Outcome in Neuroblastoma Isabelle Janoueix-Lerosey, Gudrun …

A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t (X; 17)(p11. 2; q23)

P Argani, MY Lui, J Couturier, R Bouvier, JC Fournet… - Oncogene, 2003 - nature.com
A distinctive subset of renal carcinomas is associated with Xp11. 2 translocations and
resulting TFE3 gene fusions (PRCC–TFE3, PSF–TFE3, NONO–TFE3, ASPL–TFE3) …

Merkel cell carcinoma of the skin: pathological and molecular evidence for a causative role of MCV in oncogenesis

X Sastre‐Garau, M Peter, MF Avril… - The Journal of …, 2009 - Wiley Online Library
Merkel cell carcinoma (MCC), a skin tumour with neuroendocrine features, was recently
found to be associated with a new type of human polyomavirus, called Merkel cell virus …

[PDF][PDF] Accumulation of segmental alterations determines progression in neuroblastoma

G Schleiermacher, I Janoueix-Lerosey… - Journal of Clinical …, 2010 - researchgate.net
Purpose Neuroblastoma is characterized by two distinct types of genetic profiles, consisting
of either numerical or segmental chromosome alterations. The latter are associated with a …

Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors

F Némati, X Sastre-Garau, C Laurent, J Couturier… - Clinical cancer …, 2010 - AACR
Purpose: Uveal melanoma is the most common primary intraocular malignant tumor in
adults and is defined by a poor natural outcome, as 50% of patients die from metastases …

High PTP4A3 phosphatase expression correlates with metastatic risk in uveal melanoma patients

C Laurent, F Valet, N Planque, L Silveri, S Maacha… - Cancer research, 2011 - AACR
A high percentage of uveal melanoma patients develop metastatic tumors predominantly in
the liver. We studied the molecular profiles derived from gene expression microarrays and …

[HTML][HTML] A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

J Liu, D Ottaviani, M Sefta, C Desbrousses… - Nature …, 2021 - nature.com
Retinoblastoma is the most frequent intraocular malignancy in children, originating from a
maturing cone precursor in the developing retina. Little is known on the molecular basis …