Sequence-and target-independent angiogenesis suppression by siRNA via TLR3
ME Kleinman, K Yamada, A Takeda… - Nature, 2008 - nature.com
Clinical trials of small interfering RNA (siRNA) targeting vascular endothelial growth factor-A
(VEGFA) or its receptor VEGFR1 (also called FLT1), in patients with blinding choroidal …
(VEGFA) or its receptor VEGFR1 (also called FLT1), in patients with blinding choroidal …
Drusen complement components C3a and C5a promote choroidal neovascularization
M Nozaki, BJ Raisler, E Sakurai… - Proceedings of the …, 2006 - National Acad Sciences
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
industrialized nations, affecting 30–50 million people worldwide. The earliest clinical …
industrialized nations, affecting 30–50 million people worldwide. The earliest clinical …
Corneal avascularity is due to soluble VEGF receptor-1
Corneal avascularity—the absence of blood vessels in the cornea—is required for optical
clarity and optimal vision, and has led to the cornea being widely used for validating pro-and …
clarity and optimal vision, and has led to the cornea being widely used for validating pro-and …
Enlargement of foveal avascular zone in diabetic eyes evaluated by en face optical coherence tomography angiography
N Takase, M Nozaki, A Kato, H Ozeki, M Yoshida… - Retina, 2015 - journals.lww.com
Purpose: To evaluate the area of the foveal avascular zone (FAZ) detected by en face OCTA
(AngioVue, Avanti OCT; Optovue) in healthy and diabetic eyes. Methods: Retrospective …
(AngioVue, Avanti OCT; Optovue) in healthy and diabetic eyes. Methods: Retrospective …
CCR3 is a target for age-related macular degeneration diagnosis and therapy
A Takeda, JZ Baffi, ME Kleinman, WG Cho, M Nozaki… - Nature, 2009 - nature.com
Age-related macular degeneration (AMD), a leading cause of blindness worldwide, is as
prevalent as cancer in industrialized nations. Most blindness in AMD results from invasion of …
prevalent as cancer in industrialized nations. Most blindness in AMD results from invasion of …
Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema
S Yoshida, T Murakami, M Nozaki, K Suzuma… - Graefe's Archive for …, 2021 - Springer
Diabetic macular edema (DME), characterized by exudative fluid accumulation in the
macula, is the most common form of sight-threatening retinopathy in patients with diabetes …
macula, is the most common form of sight-threatening retinopathy in patients with diabetes …
[HTML][HTML] New insights into microaneurysms in the deep capillary plexus detected by optical coherence tomography angiography in diabetic macular edema
N Hasegawa, M Nozaki, N Takase… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: To study the association between the distributions of microaneurysms detected by
en face optical coherence tomography angiography (OCTA) and diabetic macular edema …
en face optical coherence tomography angiography (OCTA) and diabetic macular edema …
Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth
WG Cho, RJC Albuquerque… - Proceedings of the …, 2009 - National Acad Sciences
Neovascularization in response to tissue injury consists of the dual invasion of blood
(hemangiogenesis) and lymphatic (lymphangiogenesis) vessels. We reported recently that …
(hemangiogenesis) and lymphatic (lymphangiogenesis) vessels. We reported recently that …
[HTML][HTML] The role of laser photocoagulation in treating diabetic macular edema in the era of intravitreal drug administration: A descriptive review
M Nozaki, R Ando, T Kimura, F Kato, T Yasukawa - Medicina, 2023 - mdpi.com
Background and Objectives: This study aimed to elucidate the role of laser photocoagulation
therapy in the treatment of diabetic macular edema (DME) as an alternative to, or in …
therapy in the treatment of diabetic macular edema (DME) as an alternative to, or in …
[HTML][HTML] Characteristics of polypoidal choroidal vasculopathy evaluated by optical coherence tomography angiography
T Tomiyasu, M Nozaki, M Yoshida… - … ophthalmology & visual …, 2016 - iovs.arvojournals.org
Purpose: The purpose of this study was to compare the angiographic findings of polypoidal
choroidal vasculopathy (PCV) detected by indocyanine green angiography (ICGA) and en …
choroidal vasculopathy (PCV) detected by indocyanine green angiography (ICGA) and en …