User profiles for "author:P Groscurth"

Peter Groscurth

Professor of Anatomy em., University of Zurich
Verified email at anatomy.uzh.ch
Cited by 10620

Morphological features of cell death

U Ziegler, P Groscurth - Physiology, 2004 - journals.physiology.org
Cell death is discriminated into two main forms: apoptosis and necrosis. In contrast to
necrosis, apoptosis is a regulated, energy-dependent form of cell death leading to …

Embryoid bodies: an in vitro model of mouse embryogenesis

I Desbaillets, U Ziegler, P Groscurth… - Experimental …, 2000 - cambridge.org
Embryonic stem (ES) cells are pluripotent cells isolated from the inner cell mass of
blastocysts. ES cells are able to differentiate into the three primitive layers (endoderm …

Architecture of arachnoid trabeculae, pillars, and septa in the subarachnoid space of the human optic nerve: anatomy and clinical considerations

…, HR Laeng, J Flammer, P Groscurth - British Journal of …, 2003 - bjo.bmj.com
Aims: To describe the anatomy and the arrangement of the arachnoid trabeculae, pillars,
and septa in the subarachnoid space of the human optic nerve and to consider their …

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

K Frei, C Siepl, P Groscurth, S Bodmer… - European journal of …, 1987 - Wiley Online Library
In this study microglial cells isolated from brain cell cultures of newborn mice were
characterized and investigated for morphology, their responses to growth factors and their …

Killing mechanisms of cytotoxic T lymphocytes

P Groscurth, L Filgueira - Physiology, 1998 - journals.physiology.org
Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including
exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO …

Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity

T Glaser, S Winter, P Groscurth, H Safayhi… - British journal of …, 1999 - nature.com
Steroids are essential for the control of oedema in human malignant glioma patients but may
interfere with the efficacy of chemotherapy. Boswellic acids are phytotherapeutic anti …

Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function

U Wüllner, J Seyfried, P Groscurth, S Beinroth, S Winter… - Brain research, 1999 - Elsevier
Glutathione (GSH) levels are supposed to determine the vulnerability of many cells towards
a wide array of insults. We investigated the effects of chronic inhibition of GSH synthesis and …

Distinction of apoptotic and necrotic cell death by in situ labelling of fragmented DNA

M Kressel, P Groscurth - Cell and tissue research, 1994 - Springer
The occurrence and spatial distribution of intracellular DNA fragmentation was investigated
by in situ 3′ end labelling of DNA breaks in K562 cells treated in such a way to cause either …

Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia

…, R Lehmann, M Gassmann, P Groscurth… - Cell …, 2005 - journals.sagepub.com
A variety of explanations have been provided to elucidate the requirement of the large islet
mass that is essential for a successful treatment of patients with type I diabetes by …

Selective extradural anterior clinoidectomy for supra-and parasellar processes

…, K Strommer, TE Kwak, P Roth, P Groscurth - Journal of …, 1997 - thejns.org
✓ Removal of the anterior clinoid process (ACP) facilitates radical removal of tumors or
radical neck clipping of aneurysms in the supra-and parasellar regions by providing a wide …