Age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …
Dietary ω-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: a systematic review and meta-analysis
Objective To systematically review the evidence on dietary ω-3 fatty acid and fish intake in
the primary prevention of age-related macular degeneration (AMD). Methods Seven …
the primary prevention of age-related macular degeneration (AMD). Methods Seven …
Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis
Objective To evaluate the effectiveness of dietary antioxidants in the primary prevention of
age related macular degeneration (AMD). Design Systematic review and meta-analysis …
age related macular degeneration (AMD). Design Systematic review and meta-analysis …
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …
A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy
Abstract Malattia Leventinese (ML) and Doyne honeycomb retinal dystrophy (DHRD) refer to
two autosomal dominant diseases characterized by yellow-white deposits known as drusen …
two autosomal dominant diseases characterized by yellow-white deposits known as drusen …
Safety and efficacy of a flexible dosing regimen of ranibizumab in neovascular age-related macular degeneration: the SUSTAIN study
Objective To evaluate the safety and efficacy of individualized ranibizumab treatment in
patients with neovascular age-related macular degeneration. Design Twelve-month, phase …
patients with neovascular age-related macular degeneration. Design Twelve-month, phase …
Automatic segmentation of nine retinal layer boundaries in OCT images of non-exudative AMD patients using deep learning and graph search
We present a novel framework combining convolutional neural networks (CNN) and graph
search methods (termed as CNN-GS) for the automatic segmentation of nine layer …
search methods (termed as CNN-GS) for the automatic segmentation of nine layer …
Tolerating subretinal fluid in neovascular age-related macular degeneration treated with ranibizumab using a treat-and-extend regimen: FLUID study 24-month results
RH Guymer, CM Markey, IL McAllister, MC Gillies… - Ophthalmology, 2019 - Elsevier
Purpose To test the hypothesis that tolerating some subretinal fluid (SRF) in patients with
neovascular age-related macular degeneration (nAMD) treated with ranibizumab using a …
neovascular age-related macular degeneration (nAMD) treated with ranibizumab using a …
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration
Y Yu, TR Bhangale, J Fagerness, S Ripke… - Human molecular …, 2011 - academic.oup.com
Despite significant progress in the identification of genetic loci for age-related macular
degeneration (AMD), not all of the heritability has been explained. To identify variants which …
degeneration (AMD), not all of the heritability has been explained. To identify variants which …
[HTML][HTML] First-in-human trial of a novel suprachoroidal retinal prosthesis
Retinal visual prostheses (“bionic eyes”) have the potential to restore vision to blind or
profoundly vision-impaired patients. The medical bionic technology used to design …
profoundly vision-impaired patients. The medical bionic technology used to design …