Emerging pathogens

J Ponton, R Rüchel, KV Clemons, DC Coleman… - …, 2000 - academic.oup.com
The ever increasing numbers of immunosuppressed individuals has led to a significant
increase in the incidence of opportunistic infections, particularly those caused by fungi. The …

A comparison of secretory proteinases from different strains of Candida albicans

R Rüchel, R Tegeler, M Trost - Sabouraudia: Journal of Medical …, 1982 - Taylor & Francis
Randomly selected strains of Candida albicans were grown with bovine serum albumin
(BSA) as a single nitrogen source. From all strains tested, culture supernatant contained …

Candida acid proteinases

R Rüchel, F De Bernardis, TL Ray… - Journal of Medical …, 1992 - Taylor & Francis
In contrast to many well documented pathogenic bacteria, the pathogenic Candida species
are not characterized by dominant virulence factors. However, the recognized order of …

Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue

…, H Eiffert, F Staib, R Rüchel - Journal of medical …, 1990 - microbiologyresearch.org
A serine proteinase (Alp) from the culture supernate of a clinical isolate of Aspergillus
fumigatus was purified to virtual homogeneity at a yield of 41%. The procedure involved …

Cleavage of immunoglobulins by pathogenic yeasts of the genus Candida.

R Rüchel - Microbiological sciences, 1986 - europepmc.org
The yeast-like fungi Candida albicans and Candida tropicalis are opportunistic pathogens
which are distinguished from less virulent yeasts by the secretion of acid proteases. Candida …

Expression of extracellular acid proteinase by proteolytic Candida spp. during experimental infection of oral mucosa

M Borg, R Rüchel - Infection and Immunity, 1988 - Am Soc Microbiol
We traced an acid proteinase from Candida spp. in the initial stages of the pathogenesis of
the mycosis. On infection of human buccal mucosa, proteinase antigens were detected by …

Epidemiology and antifungal susceptibilities of Candida spp. to six antifungal agents: results from a surveillance study on fungaemia in Germany from July 2004 to …

MB Zepelin, L Kunz, R Rüchel… - Journal of …, 2007 - academic.oup.com
Objectives Data on fungal infections occurring in Germany are rare to date. The aim of the
present study was to survey the epidemiological situation in Germany, to provide data on the …

Transmission-electron microscopic observations of freeze-etched polyacrylamide gels

R Rüchel, RL Steere, EF Erbe - Journal of Chromatography A, 1978 - Elsevier
Structures of polyacrylamide gels were examined by transmission-electron microscopy of
freeze-etched specimens. This experimental approach allows higher resolution than that …

Bacterial flora accompanying Candida yeasts in clinical specimens

C Hermann, J Hermann, U Munzel, R Rüchel - Mycoses, 1999 - Wiley Online Library
From 1986 to 1988, in the pre‐fluconazole era, 67 765 clinical specimens from the Göttingen
University Hospital were investigated for bacteria and fungi in our institution. Oral and throat …

Properties of a purified proteinase from the yeast Candida albicans

R Rüchel - Biochimica et Biophysica Acta (BBA)-Enzymology, 1981 - Elsevier
The proteinase from culture supernatants of Candida albicans strain CBS-2730 was purified
virtually to homogeneity by ion-exchange chromatography and affinity chromatography. The …