Inhibition of pyruvate dehydrogenase kinase as a therapeutic strategy against cancer

S Sradhanjali, MM Reddy - Current topics in medicinal …, 2018 - ingentaconnect.com
Cancer cells alter their metabolism to support the uninterrupted supply of biosynthetic
molecules required for continuous proliferation. Glucose metabolism is frequently …

[HTML][HTML] Aurora kinase B expression, its regulation and therapeutic targeting in human retinoblastoma

NA Borah, S Sradhanjali, MR Barik… - … & Visual Science, 2021 - tvst.arvojournals.org
Purpose: Aurora kinase B (AURKB) plays a pivotal role in the regulation of mitosis and is
gaining prominence as a therapeutic target in cancers; however, the role of AURKB in …

[HTML][HTML] Overexpression of pyruvate dehydrogenase kinase 1 in retinoblastoma: A potential therapeutic opportunity for targeting vitreous seeds and hypoxic regions

S Sradhanjali, D Tripathy, S Rath, R Mittal, MM Reddy - PLoS One, 2017 - journals.plos.org
Pyruvate dehydrogenase kinase 1 (PDK1), a key enzyme implicated in metabolic
reprogramming of tumors, is induced in several tumors including glioblastoma, breast …

In vitro synergy of natamycin and voriconazole against clinical isolates of Fusarium, Candida, Aspergillus and Curvularia spp

S Sradhanjali, B Yein, S Sharma, S Das - British Journal of …, 2018 - bjo.bmj.com
Aim To determine the minimum inhibitory concentrations (MICs) of voriconazole and
natamycin, alone and in combination, against the clinical isolates of Fungus and to evaluate …

[HTML][HTML] The Oncogene MYCN Modulates Glycolytic and Invasive Genes to Enhance Cell Viability and Migration in Human Retinoblastoma

S Sradhanjali, P Rout, D Tripathy, S Kaliki, S Rath… - Cancers, 2021 - mdpi.com
Simple Summary Retinoblastoma (RB) is a cancer in children, caused by loss of function of
RB1 gene. Additional factors such as increase in gene copy numbers of oncogenes MYCN …

A prospective two-year longitudinal follow-up study depicting humoral and cell-mediated immune responses in Covaxin vaccinated individuals

A Tripathy, S Podder, S Sradhanjali, D Bhattacharya… - medRxiv, 2023 - medrxiv.org
There are majorly two variants of SARS-CoV-2 vaccine that were employed worldwide on
emergency basis to contain the COVID-19 pandemic ie, RNA based or adenovirus construct …

In vitro synergy of natamycin and voriconazole against clinical isolates of Fusarium, Candida, Aspergillus and Curvularia spp.

SS Swatishree Sradhanjali, BY Bandana Yein… - 2018 - cabidigitallibrary.org
Aim: To determine the minimum inhibitory concentrations (MICs) of voriconazole and
natamycin, alone and in combination, against the clinical isolates of Fungus and to evaluate …

[CITATION][C] The Role of Mycn in Regulating Metabolic Reprogramming In Retinoblastoma

S Sradhanjali - shodhganga.inflibnet.ac.in
Shodhganga@INFLIBNET: The Role of Mycn in Regulating Metabolic Reprogramming In
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