Diabetic retinal disease is envisioned to become the plague of the coming decades with a
steep increase of worldwide diabetes incidence followed by a substantial rise in retinal …

Age-related macular degeneration, especially the neovascular form of the disease, is the
leading cause of blindness in elderly people in developed countries. Thermal …

Age-related macular degeneration (AMD) is still referred to as the leading cause of severe
and irreversible visual loss world-wide. The disease has a profound effect on quality of life of …

OBJECTIVE: Two similarly designed, phase-3 studies (VEGF Trap-Eye: Investigation of
Efficacy and Safety in Wet AMD [VIEW 1, VIEW 2]) of neovascular age-related macular …

Obtaining models that capture imaging markers relevant for disease progression and
treatment monitoring is challenging. Models are typically based on large amounts of data …

Objective To demonstrate superiority of ranibizumab 0.5 mg monotherapy or combined with
laser over laser alone based on mean average change in best-corrected visual acuity …

Purpose Two similarly designed phase 3 trials (HAWK and HARRIER) compared
brolucizumab, a single-chain antibody fragment that inhibits vascular endothelial growth …

Obtaining expert labels in clinical imaging is difficult since exhaustive annotation is time-
consuming. Furthermore, not all possibly relevant markers may be known and sufficiently …

Purpose A head-to-head comparison was performed between vascular endothelial growth
factor blockade and laser for treatment of diabetic macular edema (DME). Design Two …

Purpose To determine efficacy and safety of intravitreal aflibercept in patients with
neovascular age-related macular degeneration (AMD) during a second year of variable …