User profiles for "author:Yih-Chung Tham"

Yih Chung Tham

Yong Loo Lin School of Medicine, National University of Singapore; Singapore Eye …
Verified email at nus.edu.sg
Cited by 17504

Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis

YC Tham, X Li, TY Wong, HA Quigley, T Aung… - Ophthalmology, 2014 - Elsevier
Purpose Glaucoma is the leading cause of global irreversible blindness. Present estimates
of global glaucoma prevalence are not up-to-date and focused mainly on European ancestry …

Global prevalence of diabetic retinopathy and projection of burden through 2045: systematic review and meta-analysis

ZL Teo, YC Tham, M Yu, ML Chee, TH Rim, N Cheung… - Ophthalmology, 2021 - Elsevier
Topic To provide updated estimates on the global prevalence and number of people with
diabetic retinopathy (DR) through 2045. Clinical Relevance The International Diabetes …

[HTML][HTML] Applications of digital health for public health responses to COVID-19: a systematic scoping review of artificial intelligence, telehealth and related technologies

DV Gunasekeran, RMWW Tseng, YC Tham… - NPJ digital …, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has overwhelmed healthcare
services, faced with the twin challenges in acutely meeting the medical needs of patients …

Logistic regression was as good as machine learning for predicting major chronic diseases

S Nusinovici, YC Tham, MYC Yan, DSW Ting… - Journal of clinical …, 2020 - Elsevier
Objective To evaluate the performance of machine learning (ML) algorithms and to compare
them with logistic regression for the prediction of risk of cardiovascular diseases (CVDs) …

[HTML][HTML] Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome …

E Wheeler, A Leong, CT Liu, MF Hivert… - PLoS …, 2017 - journals.plos.org
Background Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and
assess glycemic control in patients with diabetes. Previous genome-wide association …

[HTML][HTML] A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study

CY Cheung, AR Ran, S Wang, VTT Chan… - The Lancet Digital …, 2022 - thelancet.com
Background There is no simple model to screen for Alzheimer's disease, partly because the
diagnosis of Alzheimer's disease itself is complex—typically involving expensive and …

[HTML][HTML] Benchmarking large language models' performances for myopia care: a comparative analysis of ChatGPT-3.5, ChatGPT-4.0, and Google Bard

ZW Lim, K Pushpanathan, SME Yew, Y Lai, CH Sun… - …, 2023 - thelancet.com
Summary Background Large language models (LLMs) are garnering wide interest due to
their human-like and contextually relevant responses. However, LLMs' accuracy across …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre

CY Cheung, D Xu, CY Cheng… - Nature biomedical …, 2021 - nature.com
Retinal blood vessels provide information on the risk of cardiovascular disease (CVD). Here,
we report the development and validation of deep-learning models for the automated …

Glaucoma in Asia: regional prevalence variations and future projections

EW Chan, X Li, YC Tham, J Liao, TY Wong… - British Journal of …, 2016 - bjo.bmj.com
Purpose To evaluate glaucoma prevalence and disease burden across Asian subregions
from 2013 to 2040. Methods We conducted a systematic review and meta-analysis of 23 …