Age-related macular degeneration is a leading cause of visual impairment and severe vision
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …

Central serous chorioretinopathy (CSCR) is a common retinal cause of vision loss. This
review surveys the epidemiology, risk factors, clinical presentation, natural history and …

Background: Retinal vessel caliber may be a novel marker of coronary heart disease (CHD)
risk. However, the sex-specific effect, magnitude of association, and effect independent of …

Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …

Objectives To report on the causes of blindness certifications in England and Wales in
working age adults (16–64 years) in 2009–2010; and to compare these with figures from …

Aims The retinal microvasculature may reflect pre-clinical changes in the cerebral and
coronary microcirculations. We assessed whether smaller retinal arterioles and larger …

Aims/hypothesis This study was designed to determine whether the relationship of glycated
haemoglobin to diabetic microvascular complications shows any natural thresholds that …

The caliber of the retinal vessels has been shown to be associated with stroke events.
However, the consistency and magnitude of association, and the changes in predicted risk …

The microcirculation is relatively inaccessible to direct visualization and investigation.
Recent methods have been developed which use advanced retinal photographic imaging …

Summary Background The WHO and American Diabetes Association criteria for diagnosing
diabetes mellitus assume the presence of a glycaemic threshold with high sensitivity for …