User profiles for "author:Michel Michaelides"
Michel MichaelidesUCL Institute of Ophthalmology and Moorfields Eye Hospital Verified email at ucl.ac.uk Cited by 21202 |
Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options
P Tanna, RW Strauss, K Fujinami… - British Journal of …, 2017 - bjo.bmj.com
Stargardt disease (STGD1; MIM 248200) is the most prevalent inherited macular dystrophy
and is associated with disease-causing sequence variants in the gene ABCA4. Significant …
and is associated with disease-causing sequence variants in the gene ABCA4. Significant …
Leber congenital amaurosis/early-onset severe retinal dystrophy: clinical features, molecular genetics and therapeutic interventions
N Kumaran, AT Moore, RG Weleber… - British journal of …, 2017 - bjo.bmj.com
Leber congenital amaurosis (LCA) and early-onset severe retinal dystrophy (EOSRD) are
both genetically and phenotypically heterogeneous, and characterised clinically by severe …
both genetically and phenotypically heterogeneous, and characterised clinically by severe …
The cone dysfunction syndromes
M Michaelides, DM Hunt, AT Moore - British Journal of Ophthalmology, 2004 - bjo.bmj.com
The cone dystrophies comprise a heterogeneous group of disorders characterised by visual
loss, abnormalities of colour vision, central scotomata, and a variable degree of nystagmus …
loss, abnormalities of colour vision, central scotomata, and a variable degree of nystagmus …
[HTML][HTML] Long-term effect of gene therapy on Leber's congenital amaurosis
JWB Bainbridge, MS Mehat, V Sundaram… - … England Journal of …, 2015 - Mass Medical Soc
Background Mutations in RPE65 cause Leber's congenital amaurosis, a progressive retinal
degenerative disease that severely impairs sight in children. Gene therapy can result in …
degenerative disease that severely impairs sight in children. Gene therapy can result in …
A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study): 12-month data: report 2
M Michaelides, A Kaines, RD Hamilton, S Fraser-Bell… - Ophthalmology, 2010 - Elsevier
PURPOSE: To report the findings at 1 year of a study comparing repeated intravitreal
bevacizumab (ivB) and modified Early Treatment of Diabetic Retinopathy Study (ETDRS) …
bevacizumab (ivB) and modified Early Treatment of Diabetic Retinopathy Study (ETDRS) …
A comparison of the causes of blindness certifications in England and Wales in working age adults (16–64 years), 1999–2000 with 2009–2010
G Liew, M Michaelides, C Bunce - BMJ open, 2014 - bmjopen.bmj.com
Objectives To report on the causes of blindness certifications in England and Wales in
working age adults (16–64 years) in 2009–2010; and to compare these with figures from …
working age adults (16–64 years) in 2009–2010; and to compare these with figures from …
A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data …
R Rajendram, S Fraser-Bell, A Kaines… - Archives of …, 2012 - jamanetwork.com
Objective To report the 2-year outcomes of the BOLT study, a prospective randomized
controlled trial evaluating intravitreous bevacizumab and modified Early Treatment Diabetic …
controlled trial evaluating intravitreous bevacizumab and modified Early Treatment Diabetic …
[PDF][PDF] Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease
Inherited retinal disease is a common cause of visual impairment and represents a highly
heterogeneous group of conditions. Here, we present findings from a cohort of 722 …
heterogeneous group of conditions. Here, we present findings from a cohort of 722 …
[HTML][HTML] Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice
Familial macular degeneration is a clinically and genetically heterogeneous group of
disorders characterized by progressive central vision loss. Here we show that an R373C …
disorders characterized by progressive central vision loss. Here we show that an R373C …
Progressive cone and cone-rod dystrophies: phenotypes and underlying molecular genetic basis
The cone and cone–rod dystrophies form part of a heterogeneous group of retinal disorders
that are an important cause of visual impairment in children and adults. There have been …
that are an important cause of visual impairment in children and adults. There have been …