Context Low birth weight is implicated as a risk factor for type 2 diabetes. However, the
strength, consistency, independence, and shape of the association have not been …

Objective. To examine the influence of initial infant feeding on obesity in later life. Methods.
A systematic review of published studies investigating the association between infant …

Background The relevance to coronary heart disease (CHD) of cytokines that govern
inflammatory cascades, such as interleukin-6 (IL-6), may be underestimated because such …

Background Although 10 000 steps per day is widely promoted to have health benefits, there
is little evidence to support this recommendation. We aimed to determine the association …

Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to
assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3 …

Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …

Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …

Objective: To determine the risk factors for non-insulin dependent diabetes in a cohort
representative of middle aged British men. Design: Prospective study. Subjects and setting …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Background Clinical use of criteria for metabolic syndrome to simultaneously predict risk of
cardiovascular disease and diabetes remains uncertain. We investigated to what extent …