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Optical coherence tomography angiography characteristics of polypoidal choroidal vasculopathy
  1. Mayer Srour,
  2. Giuseppe Querques,
  3. Oudy Semoun,
  4. Ala El Ameen,
  5. Alexandra Miere,
  6. Anne Sikorav,
  7. Olivia Zambrowski,
  8. Eric H Souied
  1. Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France
  1. Correspondence to Professor Eric H Souied, Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, 40 Avenue de Verdun, Créteil 94000, France; eric.souied{at}


Purpose To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A).

Methods Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral-domain OCT and OCT-A.

Results Twelve eyes of 12 patients (mean age 72.6±10.5 years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyperflow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyperflow round structure, surrounded by a hypointense halo, and in 9/12 eyes (75%) a hypoflow round structure.

Conclusions The OCT-A is a non-invasive imaging modality allowing the visualisation of different structures in PCV. The BVN is constantly clearly detected. The hypoflow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the BVN. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV.

  • Imaging
  • Neovascularisation
  • Retina
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  • Contributors Design and conduct of the study: MS, GQ and EHS. Collection, management and analysis: MS, GQ, AEA, OS and EHS; interpretation of the data: MS, GQ and EHS and preparation, review or approval of the manuscript: MS, GQ, AEA, OS, AM, AS, OZ and EHS.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval Ethic Committee of Centre Hospitalier Intercommunal de Créteil.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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