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Highlights from this issue
  1. Keith Barton1,
  2. James Chodosh2,
  3. Jost B Jonas, Editors in Chief3
  1. 1Moorfields Eye Hospital, London, UK
  2. 2Ophthalmology, Massachusetts Eye and Ear Infirmary Howe Laboratory, Harvard Medical School, Boston, Massachusetts, USA
  3. 3Department of Ophthalmology, Ruprecht-Karls-University Heidelberg, Seegartenklinik Heidelberg, Mannheim, Germany
  1. Correspondence to Keith Barton; BJO{at}

Statistics from

Comparison of corneal endothelial cell density and morphology after posterior chamber phakic intraocular lens implantation with and without a central hole (see page 1461)

Phakic posterior chamber lens implantation using implants containing a central hole may be better than those without, but possibly only in terms of avoiding laser iridotomies and thereby minimising trauma to corneal endothelium.

The Malaysian cataract surgery registry: risk indicators for posterior capsular rupture (see page 1466)

The rate of posterior capsule rupture was observed to be higher with advancing age, male gender, presence of pseudoexfoliation, phacomorphic lens morphology, diabetes mellitus, renal failure, vitreo-retinal surgery and less experienced surgeons. Interestingly extracapsular cataract extraction and kinetic (topical or intracameral) anaesthesia were associated with lower posterior capsule rupture rates.

Predictive factors for the placebo effect in clinical trials for dry eye: a pooled analysis of three clinical trials (see page 1471)

We investigated the predictors of the placebo response in dry eye clinical trials. Patients with high baseline scores or aged over 40 years were more likely to exhibit a stronger placebo response.

Intereye asymmetry in bilateral keratoconus, keratoconus suspect, and normal eyes and its relationship with disease severity (see page 1475)

Asymmetry between fellow eyes in keratoconus was associated with disease severity and could effectively discriminate keratoconic from normal eyes.

Evolving risk factors and antibiotic sensitivity patterns for microbial keratitis at a large county hospital (see page 1483)

In a survey of microbial keratitis in Texas, Gram-negative organisms were sensitive to ceftazidime, tobramycin, and fluoroquinolones while gram-positive organisms exhibited a wide …

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