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Posner-Schlossman syndrome in Wenzhou, China: a retrospective review study
  1. Jun Hong Jiang1,
  2. Shao Dan Zhang2,
  3. Ma Li Dai1,
  4. Juan Yuan Yang1,
  5. Yan Qian Xie1,
  6. Cheng Hu1,
  7. Guang Yun Mao1,
  8. Fan Lu1,
  9. Yuan Bo Liang1,3,4
  1. 1 The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China
  2. 2 Department of Ophthalmology, The Fourth People’s Hospital of Shenyang, Shenyang Key Laboratory of Ophthalmology, Shenyang, Liaoning Province, China
  3. 3 School of Medicine, Dentistry and Biomedical Sciences, Queen‘s University, Belfast, United Kingdom
  4. 4 Centre for Public Health, Health Services and Primary Care, Queen‘s University, Belfast, United Kingdom
  1. Correspondence to Dr Yuan Bo Liang, The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; yuanboliang{at}


Aim To describe the incidence of Posner-Schlossman syndrome (PSS) in Lucheng District, Wenzhou, China, over a 10-year period.

Methods We reviewed retrospectively the medical records of all inpatient and outpatient patients diagnosed with PSS during the years 2005–2014 in the Eye Hospital of Wenzhou Medical University. The keywords of ‘glaucomatocyclitic crisis’, ‘Posner-Schlossman syndrome’ and ‘PSS’ were used for the retrieval. Only patients with registered residing address in Lucheng District where the hospital located were finally selected. The cumulative incidence and annual incidence of PSS were calculated based on the sum of household registered population and temporary resident population in Lucheng District.

Results A total of 576 patients with PSS (339 men and 237 women) met the retrieval criteria. The mean age of these subjects at the first clinic visit was 40±15 years. Intraocular pressure (IOP) of the initial record was 31.91±15.37 mm Hg. The 10-year cumulative incidence of PSS in Lucheng District was 39.53 per 100 000 population, whereas the mean annual incidence of PSS in this area was 3.91 per 100 000 population. The majority of these patients were aged 20–59 years (83.9%). Men showed a significantly higher cumulative incidence of PSS than women (p=0.010). Higher rate of newly onset cases was found in spring (31%) than in other seasons (p=0.006).

Conclusions Our results suggest a relatively high incidence of PSS in Wenzhou, a southeastern city in China. Young, male adults are prone to be affected in spring. However, the aetiology and other risk factors are still waited to be clarified.

  • Epidemiology
  • Intraocular pressure
  • Inflammation

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  • Contributors YBL: involved in design of study; JHJ and YBL: conduct of study; JHJ, MLD, YQX and CH: collection of data; SDZ and YBL: management, JHJ, JYY and GYM: analysis of the data; JHJ, SDZ and YBL: interpretation of the data; JHJ, SDZ and YBL: preparation of the manuscript; YBL and FL: provision of materials and resources; and YBL, FL and SDZ: review and approval of the manuscript.

  • Competing interests None declared.

  • Patient consent As this was a retrospective study with de-identified data, informed consent was not required.

  • Ethics approval This study was approved by the Ethics Committee of the Wenzhou Medical University.

  • Provenance and peer review Not commissioned; externally peer reviewed.