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Uveitis and health disparities: results from the National Inpatient Sample
  1. Krati Chauhan1,
  2. Steven Scaife2,
  3. James T Rosenbaum3,4
  1. 1 Division of Rheumatology, Southern Illinois University – School of Medicine, Springfield, Illinois, USA
  2. 2 Center for Clinical Research, Southern Illinois University – School of Medicine, Springfield, Illinois, USA
  3. 3 Departments of Ophthalmology, Medicine, and Cell Biology, Oregon Health and Science University-School of Medicine, Portland, Oregon, USA
  4. 4 Department of Ophthalmology, Legacy Devers Eye Institute, Portland, Oregon, USA
  1. Correspondence to Krati Chauhan, Division of Rheumatology, Southern Illinois University- School of Medicine, Springfield, Illinois 62702, USA; Kchauhan85{at}


Purpose Health disparities exist when the prevalence or outcome of the disease are influenced by age, race, sex or income. Health disparities are prevalent in autoimmune diseases. However, there is a lack of national US data regarding health disparities in uveitis. The primary aim of our study is to evaluate health disparities for uveitis in the USA.

Methods We performed a retrospective, observational, cross-sectional study to ascertain health disparities for uveitis and its complications in the USA using the National Inpatient Sample (NIS) for the years 2002–2013. We used the International Classification of Disease, ninth revision, codes to identify uveitis cases and ocular complications. Uveitis was divided into total, infectious and non-infectious uveitis. We collected information on age, sex, race, income quartile and ocular complications. We preformed statistical analysis using SAS V.9.4. A logistic regression model was used to predict the odds of developing uveitis and its complications.

Results There were a total of 94 143 978 discharges including 15 296 total uveitis, 4538 infectious and 10 758 non-infectious uveitis patients. Compared with the total NIS population, patients with uveitis were younger (mean age 45±18 vs 48±28 years, p value ≤0.0001, African-Americans (23% vs 10%, p value ≤0.0001), in the lowest income quartile (<$38 999; 29% vs 26%, p value ≤0.0001) and were insured by Medicaid (25% vs 20%, p value ≤0.0001).

Conclusion African-American patients have a higher prevalence of uveitis. Patients insured by Medicare and Medicaid have more frequent ocular complications. This knowledge may guide future research on disparity and shape healthcare decision making.

  • inflammation
  • public health
  • epidemiology

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  • Contributors KC and JTR were involved with the inception of the study design. SS has done the statistical analysis for the study and has provided input regarding the final draft of the manuscript. KC wrote the manuscript once the results were available. JTR has critically revised the various version of the draft written by KC, which has led to the present draft of the manuscript.

  • Funding Funding for the study was provided by Nowatski Eye Foundation. JTR gets support from NIH Grant EY RO1 026572, the William and Mary Bauman Foundation and the Stan and Madelle Rosenfeld Family Foundation.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.