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Two-year observation of posterior corneal elevations after small incision lenticule extraction (SMILE) for myopia higher than −10 dioptres
  1. Xueyi Zhou1,2,
  2. Jianmin Shang1,2,
  3. Bing Qin1,2,
  4. Yu Zhao1,2,
  5. Xingtao Zhou1,2
  1. 1 Ophthalmology, Eye and ENT Hospital of Fudan University, NHC Key Laboratory of Myopia, Shanghai, China
  2. 2 Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
  1. Correspondence to Dr Xingtao Zhou, Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200433, China; doctzhouxingtao{at}163.com

Abstract

Aim To investigate the change in posterior corneal elevations (PCEs) of eyes with extremely high myopia 2 years after small incision lenticule extraction (SMILE).

Methods We evaluated 39 eyes of 39 patients with spherical equivalent higher than −10.00 dioptres (D). Using a Scheimpflug camera (Pentacam), we measured change in PCEs at 1 day, 3 months, 6 months and 2 years after SMILE. Another 34 eyes of 34 patients who underwent femtosecond laser-assisted in situ keratomileusis (FS-LASIK) were examined before, at 1 day and long-term after surgery as the control group. For each eye, elevations at central, thinnest, maximal points and 24 other predetermined points were measured.

Results No significant forward displacements of PCEs were observed in both surgeries. The maximal but not significant forward displacement occurred around 3–6 months following SMILE, and all returned to original levels 6 months postoperatively except superior area. The peripheral area tended to displace backward, while the central area tended forwardly. In both procedures, elevations along horizontal meridians, inferior and temporal hemispheres were significantly higher than those along vertical meridians, superior and nasal hemispheres, respectively (p<0.05). Elevation on the 4 mm, 6 mm diameters at 1 day and on the 6 mm diameter and temporal hemisphere at long-term follow-up postoperatively were significantly higher in FS-LASIK than SMILE (p<0.05). Change in elevations on the 6 mm diameter circle correlated with residual bed thickness (p=0.047).

Conclusions SMILE is a safe way to correct for myopia higher than −10 D, with PCEs remaining stable 2 years after surgery.

  • optics and refraction
  • treatment surgery
  • treatment lasers

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Footnotes

  • XZ and JS contributed equally.

  • Contributors XYZ, JS and XTZ: design of the study. XYZ, JS and BQ: conduct of the study. XYZ, JS, BQ and YZ: data collection. XYZ, JS and XTZ: analysis and interpretation of data. XYZ, YZ and XTZ: edits and revisions. XTZ: final approval of article.

  • Funding This study was supported by the National Natural Science Foundation of China (Grant No. 81770955, No.81570879) and the Project of Shanghai Science and Technology (Grant No. 17140902900, No. 17411950200).

  • Competing interests None declared.

  • Patient consent for publication Not Required

  • Ethics approval This study was approved by the Ethical Committee of the Fudan University EENT Hospital Review Board.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article or uploaded as supplementary information.

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