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Congenital nasolacrimal duct obstruction continues trend for spontaneous resolution beyond first year of life
  1. Tomomichi Nakayama1,
  2. Akihide Watanabe1,
  3. Saul Rajak2,
  4. Yukito Yamanaka1,
  5. Chie Sotozono1
  1. 1 Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
  2. 2 The Sussex Eye Hospital, Brighton, UK
  1. Correspondence to Dr Akihide Watanabe, Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan; awatanab{at}


Purpose To investigate spontaneous resolution of congenital nasolacrimal duct obstruction (CNLDO) beyond 12 months of age in Japanese infants.

Methods Retrospective, observational case series. We retrospectively reviewed the clinical records of patients diagnosed with CNLDO beyond 12 months of age at Kyoto Prefectural University Hospital, Kyoto, Japan. This study involved 155 cases of CNLDO in 133 Japanese infants diagnosed with CNLDO. All patients chose intervention with either dacryoendoscopic guided probing and stenting or conservative management. The proportion and age of patients who had spontaneous CLNDO resolution were analysed.

Results The patients were divided into two groups: (1) 62 patients with 70 obstructed nasolacrimal ducts (45%) in whom spontaneous resolution occurred and (2) 71 patients with 85 obstructed nasolacrimal ducts (55%) who underwent dacryoendoscopic guided probing and stenting. The mean age of spontaneous resolution was 17.8±5.3 months (range: 12.0–35.4 months). Dacryoendoscopic guided probing and stenting were successful in 83/85 (97.6%) of cases.

Conclusions Spontaneous resolution of CNLDO can occur in 45% of infants over the age of 12 months. Dacryoendoscopic guided stenting also has high success rates in this patient group, and both treatment options can be proposed to caregivers.

  • child health (paediatrics)
  • lacrimal drainage
  • tears

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  • This study was presented as an oral presentation at the Annual Congress of Japan Clinical Ophthalmology, 12 October 2017, Tokyo, Japan.

  • Correction notice This article has been corrected since it was published Online First. Repeated content in Acknowledgement section has been removed.

  • Contributors TN and AW deigned the study. TN collected and analysed the data. TN wrote the manuscript in consultation with AW, SR, YY and CS.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data are available upon request.