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Luo et al report on expression of P63 in 85 patients with periocular and eyelid squamous cell carcinoma (SCC), and observe a correlation with a more advanced T stage and worse disease-specific survival.1 P63 has been previously reported to correlate with poor prognosis in cutaneous and head and neck SCC patients.2 3 The authors also report on Ki67 index in the same cohort of patients with periocular and eyelid SCC; Ki67 is a proliferation index and a higher Ki67 index is generally correlated with a higher mitotic rate and thus an expected worse prognosis across various …
Funding The author has not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.